143731-32-2

• 常用中文名：(S)-2-羟基对甲苯磺酸
• 常用英文名：(S)-2-FLUOROBENZHYDROL
• CAS号：143731-32-2
• 分子式：C₁₁H₁₆O₄S
• 分子量：244.30700
• 发布时间：2018-03-19 08:00:00
• 更新时间：2024-01-21 04:16:46

名称

• 中文名: (S)-2-羟基对甲苯磺酸
• 英文名: [(2S)-2-hydroxybutyl] 4-methylbenzenesulfonate
• 中文别名: (S)-2-羟基-p-甲苯磺酸丁酯
• 英文别名: (s)-2-hydroxybutyl p-tosylate

物化性质

• 密度: 1.213g/cm3
• 沸点: 390.8ºC at 760mmHg
• 分子式: C₁₁H₁₆O₄S
• 分子量: 244.30700
• 闪点: 190.1ºC
• 精确质量: 244.07700
• PSA: 71.98000
• LogP: 2.55200
• 蒸汽压: 8.3E-07mmHg at 25°C
• 折射率: 1.5165-1.5185
• 储存条件:

  密闭于0-6 ºC阴凉干燥环境中

• 稳定性:

  遵照规定使用和储存则不会分解。

• 分子结构:

  1、 摩尔折射率：61.96

  2、 摩尔体积（m³/mol）：201.2

  3、 等张比容（90.2K）：517.1

  4、 表面张力（dyne/cm）：43.5

  5、 极化率（10^-24cm³）：24.56

• 计算化学:

  1.疏水参数计算参考值（XlogP）:无

  2.氢键供体数量:1

  3.氢键受体数量:4

  4.可旋转化学键数量:5

  5.互变异构体数量:无

  6.拓扑分子极性表面积72

  7.重原子数量:16

  8.表面电荷:0

  9.复杂度:286

  10.同位素原子数量:0

  11.确定原子立构中心数量:1

  12.不确定原子立构中心数量:0

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:1

• 更多:

  1. 性状：淡黄色粘性液体

  2. 密度（g/mL,25/4℃）：无可用

  3. 相对蒸汽密度（g/mL,空气=1）：无可用

  4. 熔点（ºC）：无可用

  5. 沸点（ºC,常压）：250

  6. 沸点（ºC,5.2kPa）：无可用

  7. 折射率：1.5165-1.5185

  8. 闪点（ºC）：无可用

  9. 比旋光度（º）：无可用

  10. 自燃点或引燃温度（ºC）：无可用

  11. 蒸气压（kPa,25ºC）：无可用

  12. 饱和蒸气压（kPa,60ºC）：无可用

  13. 燃烧热（KJ/mol）：无可用

  14. 临界温度（ºC）：无可用

  15. 临界压力（KPa）：无可用

  16. 油水（辛醇/水）分配系数的对数值：无可用

  17. 爆炸上限（%,V/V）：无可用

  18. 爆炸下限（%,V/V）：无可用

  19. 溶解性：微溶于水

MSDS

Name: (S)-2-Hydroxybutyl p-tosylate 98+% Material Safety Data Sheet Synonym: None CAS: 143731-32-2 Section 1 - Chemical Product MSDS Name:(S)-2-Hydroxybutyl p-tosylate 98+% Material Safety Data Sheet Synonym:None Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 143731-32-2 (S)-2-Hydroxybutyl p-tosylate 98+ unlisted Hazard Symbols: None Listed. Risk Phrases: None Listed. Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW The toxicological properties of this material have not been fully investigated. Potential Health Effects Eye: May cause eye irritation. Skin: May cause skin irritation. Ingestion: May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated. Inhalation: May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. Chronic: No information found. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Ingestion: Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or appropriate foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Clean up spills immediately, observing precautions in the Protective Equipment section. Provide ventilation. Section 7 - HANDLING and STORAGE Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation. Storage: Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep refrigerated. (Store below 4C/39F.) Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 143731-32-2: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Liquid Color: colorless to light yellow Odor: none reported pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: > 250 deg C @ 760.00mm Hg Freezing/Melting Point: Not available. Autoignition Temperature: Not applicable. Flash Point: > 93 deg C (> 199.40 deg F) Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Not available. Solubility in water: slightly soluble Specific Gravity/Density: Not available. Molecular Formula: C11H16O4S Molecular Weight: 244.31 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Stable under normal temperatures and pressures. Conditions to Avoid: Incompatible materials, strong oxidants. Incompatibilities with Other Materials: Oxidizing agents. Hazardous Decomposition Products: Irritating and toxic fumes and gases. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 143731-32-2 unlisted. LD50/LC50: Not available. Carcinogenicity: (S)-2-Hydroxybutyl p-tosylate - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Not regulated as a hazardous material. IMO Not regulated as a hazardous material. RID/ADR Not regulated as a hazardous material. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: Not available. Risk Phrases: Safety Phrases: S 24/25 Avoid contact with skin and eyes. WGK (Water Danger/Protection) CAS# 143731-32-2: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 143731-32-2 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 143731-32-2 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A

毒性和生态

生态学数据: 通常对水是不危害的，若无政府许可，勿将材料排入周围环境。

安全

• 安全声明 (欧洲): S24/25

合成路线

73522-17-5 98-59-9 ~43% 143731-32-2

文献：Sakai, Takashi; Wada, Kou; Murakami, Takahiko; Kohra, Kiichiro; Imajo, Norihisa; et al. Bulletin of the Chemical Society of Japan, 1992 , vol. 65, # 3 p. 631 - 638

143693-24-7 ~% 143731-32-2

文献：Boaz; Zimmerman Tetrahedron Asymmetry, 1994 , vol. 5, # 2 p. 153 - 156

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