87226-41-3

• 常用中文名：(R)-(-)-Etodolac
• 常用英文名：(R)-(-)-Etodolac
• CAS号：87226-41-3
• 分子式：C₁₇H₂₁NO₃
• 分子量：287.35400
• 发布时间：2017-07-03 00:10:51
• 更新时间：2024-02-05 09:42:34

名称

• 英文名: (R)-(-)-Etodolac
• 英文别名: (S)-ethyl-9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido-[1,2,3-de]-1,4-benzoxazine-6-carboxylate; (-)-ethyl-9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido [1,2,3-de]-1,4-benzoxazine-6-carboxylate; (R)-etodolac; (S)-Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate; (R)-1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid; R-(-)-etodolic acid; (S)-9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid Ethyl Ester; ethyl (S)-(-)-9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylate; [14C]-(R)-Etodolac; (-)-etodolac

物化性质

• 密度: 1.165g/cm3
• 沸点: 452.6ºC at 760 mmHg
• 分子式: C₁₇H₂₁NO₃
• 分子量: 287.35400
• 闪点: 227.5ºC
• 精确质量: 287.15200
• PSA: 62.32000
• LogP: 3.38300
• 折射率: 1.581

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : UQ0360010 CHEMICAL NAME : Pyrano(3,4-b)indole-1-acetic acid, 1,3,4,9-tetrahydro-1,8-diethyl-, (R)- CAS REGISTRY NUMBER : 87226-41-3 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C17-H21-N-O3 MOLECULAR WEIGHT : 287.39 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 327 mg/kg TOXIC EFFECTS : Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Nutritional and Gross Metabolic - body temperature decrease REFERENCE : OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 40,737,1990

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