24796-94-9

• 常用中文名：噁嗪高氯酸盐
• 常用英文名：Oxazine 1 perchlorate
• CAS号：24796-94-9
• 分子式：C₂₀H₂₆ClN₃O₅
• 分子量：423.89100
• 相关类别： 染料试剂
• 发布时间：2018-07-20 08:44:54
• 更新时间：2024-01-04 12:56:28
• Oxazine 1 perchlorate 是一种对称阳离子染料 (λex=653 nm,λem=666 nm)。

名称

• 中文名: 恶嗪-1
• 英文名: oxazine-1 perchlorate
• 中文别名: 恶嗪 1 高氯酸盐
• 英文别名: 3,7-Bis(Diethylamino)phenoxazinum; OXAZINE 725; 3,7-BIS(DIETHYLAMINO)PHENOXAZINIUM PERCHLORATE; OXAZINE 1; Oxazine 1 perchlorate,pure,laser grade; 3,7-bis(diethylamino)phenoxazin-5-ium perchlorate; 3,7-BIS(DIETHYLAMINO)PHENOXAZONIUM PERCHLORATE; MFCD00041971; Oxazine 1 perchlorate,laser grade,pure; Oxazine 1 perchlorate

物化性质

• 分子式: C₂₀H₂₆ClN₃O₅
• 分子量: 423.89100
• 精确质量: 423.15600
• PSA: 106.55000
• LogP: 3.80510
• 储存条件:

  密闭于阴凉干燥环境中

• 稳定性:

  遵照规定使用和储存则不会分解。

• 分子结构:

  1、摩尔折射率：无可用

  2、 摩尔体积（cm³/mol）：无可用

  3、 等张比容（90.2K）：无可用

  4、 表面张力（dyne/cm）：无可用

  5、 极化率：无可用

• 计算化学:

  1、 疏水参数计算参考值（XlogP）：无可用

  2、 氢键供体数量：0

  3、 氢键受体数量：7

  4、 可旋转化学键数量：5

  5、 拓扑分子极性表面积（TPSA）：102

  6、 重原子数量：29

  7、 表面电荷：0

  8、 复杂度：629

  9、 同位素原子数量：0

  10、 确定原子立构中心数量：0

  11、 不确定原子立构中心数量：0

  12、 确定化学键立构中心数量：0

  13、 不确定化学键立构中心数量：0

  14、 共价键单元数量：2

• 更多:

  1. 性状：无可用

  2. 密度（g/mL,25/4℃）：无可用

  3. 相对蒸汽密度（g/mL,空气=1）：无可用

  4. 熔点（ºC）：无可用

  5. 沸点（ºC,常压）：无可用

  6. 沸点（ºC,5.2kPa）：无可用

  7. 折射率：无可用

  8. 闪点（ºC）：无可用

  9. 比旋光度（º）：无可用

  10. 自燃点或引燃温度（ºC）：无可用

  11. 蒸气压（kPa,25ºC）：无可用

  12. 饱和蒸气压（kPa,60ºC）：无可用

  13. 燃烧热（KJ/mol）：无可用

  14. 临界温度（ºC）：无可用

  15. 临界压力（KPa）：无可用

  16. 油水（辛醇/水）分配系数的对数值：无可用

  17. 爆炸上限（%,V/V）：无可用

  18. 爆炸下限（%,V/V）：无可用

  19. 溶解性：无可用

生物活性

• 描述: Oxazine 1 perchlorate 是一种对称阳离子染料 (λex=653 nm,λem=666 nm)。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 其他
  染料试剂
• 体外研究: 恶嗪1高氯酸盐(OX1)分别在稀水溶液中吸收并发射约653和666nm的光。它可溶于很多极性溶剂。 Oxazine 1高氯酸盐的光谱通常具有强吸收带(λmax),其在较短波长处与肩部相邻。恶嗪1高氯酸盐似乎在水溶液中以低于约1×10-4M的浓度几乎以其单体形式存在。正如预期的那样,与极性普通液体溶剂类似,Oxazine 1高氯酸盐在极性各向异性介质中仅显示单一荧光带[1]。
• 激酶实验: 恶嗪1高氯酸盐掺杂的液晶样品由一对精确夹在已知间隙的石英片制备并密封。通过毛细管作用实现在向列溶剂中引入溶解的恶嗪1高氯酸盐。对于所有液体样品，恶嗪1高氯酸盐浓度选择为1×10-5M。在向列介质中研究恶嗪1高氯酸盐，浓度为约0.1％w / w。 Oxazine 1高氯酸盐的吸收光谱在双光束分光光度计上记录，波长范围为300至800 nm，并结合电池温度控制器[1]。
• 参考文献:

  [1]. Gilani AG, et al. Estimation of ground- and excited-state dipole moments of oxazine 1 in liquid and liquid crystalline media. Spectrochim Acta A Mol Biomol Spectrosc. 2011 Jun;79(1):148-55.

MSDS

Name: Oxazine 1 perchlorate laser grade 99+% (uv-vis) Material Safety Data Sheet Synonym: CAS: 24796-94-9 Section 1 - Chemical Product MSDS Name:Oxazine 1 perchlorate laser grade 99+% (uv-vis) Material Safety Data Sheet Synonym: Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 24796-94-9 Oxazine 1 perchlorate, laser grade >99.0 246-465-5 Hazard Symbols: XI Risk Phrases: 36/37/38 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Irritating to eyes, respiratory system and skin.The toxicological properties of this material have not been fully investigated. Potential Health Effects Eye: Dust may cause mechanical irritation. The toxicological properties of this material have not been fully investigated. Skin: May cause skin irritation. The toxicological properties of this material have not been fully investigated. Ingestion: May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated. Inhalation: Dust is irritating to the respiratory tract. The toxicological properties of this substance have not been fully investigated. Chronic: No information found. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Remove contaminated clothing and shoes. Ingestion: If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing Media: Use agent most appropriate to extinguish fire. Use water spray, dry chemical, carbon dioxide, or appropriate foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Clean up spills immediately, observing precautions in the Protective Equipment section. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Avoid generating dusty conditions. Provide ventilation. Section 7 - HANDLING and STORAGE Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation. Storage: Store in a cool, dry, well-ventilated area away from incompatible substances. Keep containers tightly closed. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 24796-94-9: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Powder Color: dark green Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 198 C - 102 C Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C20H26ClN3O5 Molecular Weight: 423.89 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Stable under normal temperatures and pressures. Stability unknown. Conditions to Avoid: Incompatible materials, dust generation, strong oxidants. Incompatibilities with Other Materials: Oxidizing agents. Hazardous Decomposition Products: Hydrogen chloride, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 24796-94-9 unlisted. LD50/LC50: Not available. Carcinogenicity: Oxazine 1 perchlorate, laser grade - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Not regulated as a hazardous material. IMO Not regulated as a hazardous material. RID/ADR Not regulated as a hazardous material. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XI Risk Phrases: R 36/37/38 Irritating to eyes, respiratory system and skin. Safety Phrases: S 7/9 Keep container tightly closed and in a well-ventilated place. S 28A After contact with skin, wash immediately with plenty of water. S 33 Take precautionary measures against static discharges. S 37 Wear suitable gloves. S 37/39 Wear suitable gloves and eye/face protection. S 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). WGK (Water Danger/Protection) CAS# 24796-94-9: No information available. Canada CAS# 24796-94-9 is listed on Canada's NDSL List. CAS# 24796-94-9 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 24796-94-9 is listed on the TSCA inventory. SECTION 16 - ADDITIONAL INFORMATION N/A

毒性和生态

生态学数据: 该物质对环境可能有危害，对水体应给予特别注意。

安全

• 危害码 (欧洲): Xi: Irritant;
• 风险声明 (欧洲): 36/37/38
• 安全声明 (欧洲): 7/9-37/39-33
• 海关编码: 2934999090

合成路线

120-22-9 91-68-9 ~% 24796-94-9

文献：Journal of Medicinal Chemistry, , vol. 50, # 10 p. 2281 - 2284

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海关

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%