915763-27-8

• 常用中文名：WAY-362692
• 常用英文名：WAY-362692
• CAS号：915763-27-8
• 分子式：C₂₈H₃₅F₃N₄O₆S₂
• 分子量：644.72600
• 发布时间：2016-11-02 07:19:18
• 更新时间：2024-01-10 11:50:05
• WAY-362692 is a small molecule inhibitor of the secreted frizzled-related protein sFRP-1 with IC50 of 20 nM in FP binding assay.

名称

• 英文名: (2S)-N-(2-Methyl-2-propanyl)-2-{[4-({[5-(phenylsulfonyl)-2-(trifl uoromethyl)phenyl]sulfonyl}amino)-1-piperidinyl]carbonyl}-1-pyrro lidinecarboxamide

物化性质

• 分子式: C₂₈H₃₅F₃N₄O₆S₂
• 分子量: 644.72600
• 精确质量: 644.19500
• PSA: 153.21000
• LogP: 6.41270

合成路线

1095322-84-1 1609-86-5 ~85% 915763-27-8

文献：Moore, William J.; Kern, Jeffrey C.; Bhat, Ramesh; Commons, Thomas J.; Fukayama, Shoichi; Goljer, Igor; Krishnamurthy, Girija; Magolda, Ronald L.; Nogle, Lisa; Pitts, Keith; Stauffer, Barb; Trybulski, Eugene J.; Welmaker, Gregory S.; Wilson, Matthew; Bodine, Peter V. N. Journal of Medicinal Chemistry, 2009 , vol. 52, # 1 p. 105 - 116

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