301225-40-1

• 常用中文名：4-(2-嘧啶胺)四氢吡啶羧酸叔丁酯
• 常用英文名：TERT-BUTYL 4-(2-PYRIMIDINYLAMINO)TETRAHYDRO-1(2H)-PYRIDINECARBOXYLATE
• CAS号：301225-40-1
• 分子式：C₁₄H₂₂N₄O₂
• 分子量：278.35000
• 相关类别： 医药中间体 杂环化合物 嘧啶类化合物 胺类
• 发布时间：2017-01-08 15:35:19
• 更新时间：2024-02-04 11:36:42

名称

• 中文名: 4-(2-嘧啶胺)四氢吡啶羧酸叔丁酯
• 英文名: tert-butyl 4-(pyrimidin-2-ylamino)piperidine-1-carboxylate
• 英文别名: 4-N-(pyrimid-2-yl)amino-1-tert-butoxycarbonylpiperidine; 4-(N-(pyrimidin-2-yl)amino)-1-t-butoxycarbonylpiperidine; tert-butyl-4-(pyrimidin-2-ylamino)-1-piperidinecarboxylate; Tert-Butyl 4-(2-Pyrimidinylamino)Tetrahydro-1(2H)-Pyridinecarboxylate

物化性质

• 熔点: 132-133°C
• 分子式: C₁₄H₂₂N₄O₂
• 分子量: 278.35000
• 精确质量: 278.17400
• PSA: 67.35000
• LogP: 2.29890

安全

• 海关编码: 2933990090

合成路线

1722-12-9 87120-72-7 ~63% 301225-40-1

文献：BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BOEHRINGER INGELHEIM PHARMA GMBH and CO. KG Patent: WO2007/106705 A1, 2007 ; Location in patent: Page/Page column 102 ; WO 2007/106705 A1

79099-07-3 ~% 301225-40-1

文献：Willoughby, Christopher A.; Rosauer, Keith G.; Hale, Jeffery J.; Budhu, Richard J.; Mills, Sander G.; Chapman, Kevin T.; MacCoss, Malcolm; Malkowitz, Lorraine; Springer, Martin S.; Gould, Sandra L.; DeMartino, Julie A.; Siciliano, Salvatore J.; Cascieri, Margaret A.; Carella, Anthony; Carver, Gwen; Holmes, Karen; Schleif, William A.; Danzeisen, Renee; Hazuda, Daria; Kessler, Joseph; Lineberger, Janet; Miller, Michael; Emini, Emilio A. Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 3 p. 427 - 431

206273-87-2 ~% 301225-40-1

文献：Willoughby, Christopher A.; Rosauer, Keith G.; Hale, Jeffery J.; Budhu, Richard J.; Mills, Sander G.; Chapman, Kevin T.; MacCoss, Malcolm; Malkowitz, Lorraine; Springer, Martin S.; Gould, Sandra L.; DeMartino, Julie A.; Siciliano, Salvatore J.; Cascieri, Margaret A.; Carella, Anthony; Carver, Gwen; Holmes, Karen; Schleif, William A.; Danzeisen, Renee; Hazuda, Daria; Kessler, Joseph; Lineberger, Janet; Miller, Michael; Emini, Emilio A. Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 3 p. 427 - 431

上下游产品

上游产品  4
1722-12-9 87120-72-7 79099-07-3 206273-87-2
下游产品  1
950649-10-2

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%