79645-08-2

• 常用中文名：(+-)-Pirbuterol hydrochloride
• 常用英文名：(+-)-Pirbuterol hydrochloride
• CAS号：79645-08-2
• 分子式：C₁₂H₂₁ClN₂O₃
• 分子量：276.76000
• 发布时间：2016-08-11 13:58:54
• 更新时间：2024-03-26 19:57:44

名称

• 英文名: 2-(Hydroxymethyl)-6-{1-hydroxy-2-[(2-methyl-2-propanyl)amino]ethy l}-3-pyridinol hydrochloride (1:1)

物化性质

• 沸点: 489.3ºC at 760 mmHg
• 分子式: C₁₂H₂₁ClN₂O₃
• 分子量: 276.76000
• 闪点: 249.7ºC
• 精确质量: 276.12400
• PSA: 85.61000
• LogP: 1.89390

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : US9120000 CHEMICAL NAME : 2,6-Pyridinedimethanol, alpha-6-(((1,1-dimethylethyl)amino)methyl)-3-hydroxy- , monohydrochloride, (+-)- CAS REGISTRY NUMBER : 79645-08-2 LAST UPDATED : 199109 DATA ITEMS CITED : 6 MOLECULAR FORMULA : C12-H20-N2-O3.Cl-H MOLECULAR WEIGHT : 276.80 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 2800 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,898,1990 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 645 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,898,1990 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 53 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,898,1990 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 2500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,898,1990 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 280 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,898,1990 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 42 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,898,1990