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68252-72-2

68252-72-2结构式
68252-72-2结构式

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英文名 N-(2-Chloro-4-sulfamoylphenyl)acetamide
英文别名 Acetamide,N-(4-(aminosulfonyl)-2-chlorophenyl)
N-(4-(Aminosulfonyl)-2-chlorophenyl)acetamide
4-acetamido-3-chlorobenzenesulfonamide
PB 310
密度 1.521g/cm3
分子式 C8H9ClN2O3S
分子量 248.68700
精确质量 248.00200
PSA 101.13000
LogP 3.37640
折射率 1.615

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AB4415000
CHEMICAL NAME :
Acetamide, N-(4-(aminosulfonyl)-2-chlorophenyl)-
CAS REGISTRY NUMBER :
68252-72-2
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C8-H9-Cl-N2-O3-S
MOLECULAR WEIGHT :
248.70

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 28,1331,1978

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68252-72-2结构式

68252-72-2

文献:Ilies, Marc A.; Vullo, Daniela; Pastorek, Jaromir; Scozzafava, Andrea; Ilies, Monica; Caproiu, Miron T.; Pastorekova, Silvia; Supuran, Claudiu T. Journal of Medicinal Chemistry, 2003 , vol. 46, # 11 p. 2187 - 2196

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68252-72-2结构式

68252-72-2

文献:Ilies, Marc A.; Vullo, Daniela; Pastorek, Jaromir; Scozzafava, Andrea; Ilies, Monica; Caproiu, Miron T.; Pastorekova, Silvia; Supuran, Claudiu T. Journal of Medicinal Chemistry, 2003 , vol. 46, # 11 p. 2187 - 2196

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68252-72-2结构式

68252-72-2

文献:Ilies, Marc A.; Vullo, Daniela; Pastorek, Jaromir; Scozzafava, Andrea; Ilies, Monica; Caproiu, Miron T.; Pastorekova, Silvia; Supuran, Claudiu T. Journal of Medicinal Chemistry, 2003 , vol. 46, # 11 p. 2187 - 2196