772-31-6
772-31-6结构式
- 常用中文名：4-氟苯基环丙基甲酮
- 常用英文名：Cyclopropyl 4-fluorophenyl ketone
- CAS号：772-31-6
- 分子式：C10H9FO
- 分子量：164.176
- 相关类别： 化学试剂 有机试剂 芳香酮
- 发布时间：2018-07-29 18:44:17
- 更新时间：2024-01-03 12:02:04
| 中文名 | 4-氟苯基环丙基甲酮 |
|---|---|
| 英文名 | Cyclopropyl 4-fluorophenyl ketone |
| 中文别名 |
环丙基4-氟苯基酮
环丙基-4-氟苯基酮 |
| 英文别名 |
Cyclopropyl-(4-fluoro-phenyl)-methanone
MFCD00013728 Methanone, cyclopropyl(4-fluorophenyl)- EINECS 212-247-3 cyclopropyl-(4-fluorophenyl)methanone Cyclopropyl(4-fluorophenyl)methanone Cyclopropyl 4-fluorophenyl ketone |
| 密度 | 1.2±0.1 g/cm3 |
|---|---|
| 沸点 | 243.2±0.0 °C at 760 mmHg |
| 熔点 | -15 °C |
| 分子式 | C10H9FO |
| 分子量 | 164.176 |
| 闪点 | 100.0±0.0 °C |
| 精确质量 | 164.063736 |
| PSA | 17.07000 |
| LogP | 2.09 |
| 外观性状 | 透明非常淡黄色液体 |
| 蒸汽压 | 0.0±0.4 mmHg at 25°C |
| 折射率 | 1.560 |
| 储存条件 | 保持容器密封，储存在阴凉，干燥的地方 |
| 稳定性 | 常温常压下稳定，避免氧化物接触 |
| 分子结构 | 1、 摩尔折射率：43.47 2、 摩尔体积（m3/mol）：134.4 3、 等张比容（90.2K）：346.9 4、 表面张力（dyne/cm）：44.3 5、 介电常数： 6、 偶极距（10 -24cm 3）： 7、 极化率：17.23 |
| 计算化学 | 1.疏水参数计算参考值（XlogP）:无 2.氢键供体数量:0 3.氢键受体数量:2 4.可旋转化学键数量:2 5.互变异构体数量:2 6.拓扑分子极性表面积17.1 7.重原子数量:12 8.表面电荷:0 9.复杂度:178 10.同位素原子数量:0 11.确定原子立构中心数量:0 12.不确定原子立构中心数量:0 13.确定化学键立构中心数量:0 14.不确定化学键立构中心数量:0 15.共价键单元数量:1 |
| 更多 | 1. 性状：未确定 2. 密度（g/mL,25/4℃）：1.144 3. 相对蒸汽密度（g/mL,空气=1）：未确定 4. 熔点（ºC）：-15 °C 5. 沸点（ºC,常压）：未确定 6. 沸点（ºC, 13mm Hg）：119-120°C 7. 折射率：n 20/D 1.532 8. 闪点（º F）：212°F 9. 比旋光度（º）：未确定 10. 自燃点或引燃温度（ºC）：未确定 11. 蒸气压（kPa,25ºC）：未确定 12. 饱和蒸气压（kPa,60ºC）：未确定 13. 燃烧热（KJ/mol）：未确定 14. 临界温度（ºC）：未确定 15. 临界压力（KPa）：未确定 16. 油水（辛醇/水）分配系数的对数值：未确定 17. 爆炸上限（%,V/V）：未确定 18. 爆炸下限（%,V/V）：未确定 19. 溶解性：未确定 |
Synonym:None listed Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
Risk Phrases: None Listed. Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW
The toxicological properties of this material have not been fully investigated. Potential Health Effects Eye: May cause eye irritation. Skin: May cause skin irritation. Ingestion: May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated. Inhalation: May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. Chronic: No information found. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Ingestion: Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas. Extinguishing Media: Use agent most appropriate to extinguish fire. Use water spray, dry chemical, carbon dioxide, or appropriate foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Clean up spills immediately, observing precautions in the Protective Equipment section. Absorb spill using an absorbent, non-combustible material such as earth, sand, or vermiculite. Do not use combustible materials such as sawdust. Provide ventilation. Section 7 - HANDLING and STORAGE Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Storage: Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 772-31-6: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Clear liquid Color: clear very slight yellow Odor: None reported. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: 119.0 - 120.0 deg C @ 13.00mm Freezing/Melting Point: Not available. Autoignition Temperature: Not applicable. Flash Point: 100 deg C ( 212.00 deg F) Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Not available. Solubility in water: Not available. Specific Gravity/Density: 1.1440g/cm3 Molecular Formula: C10H9FO Molecular Weight: 164.18 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Stable under normal temperatures and pressures. Conditions to Avoid: Incompatible materials, strong oxidants. Incompatibilities with Other Materials: Strong oxidizing agents. Hazardous Decomposition Products: Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide. Hazardous Polymerization: Has not been reported. Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 772-31-6 unlisted. LD50/LC50: Not available. Carcinogenicity: Cyclopropyl 4-fluorophenyl ketone - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Not regulated as a hazardous material. IMO Not regulated as a hazardous material. RID/ADR Not regulated as a hazardous material. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: Not available. Risk Phrases: Safety Phrases: S 24/25 Avoid contact with skin and eyes. S 28A After contact with skin, wash immediately with plenty of water. S 37 Wear suitable gloves. S 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). WGK (Water Danger/Protection) CAS# 772-31-6: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 772-31-6 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 772-31-6 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A |
|
生态学数据: 对水是稍微有害的，不要让未稀释或大量的产品接触地下水，水道或者污水系统，若无政府许可，勿将材料排入周围环境
|
| 个人防护装备 | Eyeshields;Gloves |
|---|---|
| 危害码 (欧洲) | Xi |
| 安全声明 (欧洲) | S24/25 |
| 危险品运输编码 | NONH for all modes of transport |
| WGK德国 | 3 |
| 海关编码 | 2914700090 |
|
~57%
772-31-6 |
| 文献：Schliemann; Buege; Reppel Pharmazie, 1980 , vol. 35, # 3 p. 140 - 143 |
|
~%
772-31-6 |
| 文献：Chemical Communications, , vol. 49, # 32 p. 3351 - 3353 |
|
~%
772-31-6 |
| 文献：Pharmazie, , vol. 35, # 3 p. 140 - 143 |
|
~%
772-31-6 |
| 文献：Chemische Berichte, , vol. 96, p. 2532 - 2536 |
| 上游产品 5 | |
|---|---|
| 下游产品 6 | |
| 海关编码 | 2914700090 |
|---|---|
| 中文概述 | 2914700090 其他酮及醌的卤化、磺化衍生物（包括硝化和亚硝化衍生物）. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:5.5% 普通关税:30.0% |
| 申报要素 | 品名, 成分含量, 用途, 丙酮报明包装 |
| Summary | HS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0% |