160133-32-4

• 常用中文名：1-(苯基甲基)-4,4-哌啶二乙酸 4,4-二乙酯
• 常用英文名：ethyl 2-[1-benzyl-4-(2-ethoxy-2-oxoethyl)piperidin-4-yl]acetate
• CAS号：160133-32-4
• 分子式：C₂₀H₂₉NO₄
• 分子量：347.44900
• 发布时间：2018-07-31 11:29:47
• 更新时间：2024-01-10 09:16:14

名称

• 中文名: 1-(苯基甲基)-4,4-哌啶二乙酸 4,4-二乙酯
• 英文名: ethyl 2-[1-benzyl-4-(2-ethoxy-2-oxoethyl)piperidin-4-yl]acetate
• 英文别名: ethyl 2-[1-benzyl-4-(2-ethoxy-2-oxoethyl)-4-piperidyl]acetate; 4,4-Piperidinediacetic acid,1-(phenylmethyl)-,diethyl ester; Diethyl 1-benzylpiperidine-4,4-diacetate; 1-benzyl-4,4-bis-(ethoxycarbonylmethyl)-piperidine; diethyl 2,2'-(1-benzylpiperidine-4,4-diyl)diacetate

物化性质

• 分子式: C₂₀H₂₉NO₄
• 分子量: 347.44900
• 精确质量: 347.21000
• PSA: 55.84000
• LogP: 3.11310

合成路线

64-17-5 105-56-6 ~% 160133-32-4

文献：Kyorin Pharmaceutical Co., Ltd.; Nisshin Pharma Inc. Patent: EP1443046 A1, 2004 ; Location in patent: Page 186-187 ; EP 1443046 A1

3612-20-2 105-56-6 ~% 160133-32-4

文献：Merck and Company, Inc. Patent: US5776930 A1, 1998 ;

3612-20-2 ~% 160133-32-4

文献：Karl Thomae GmbH Patent: US5681841 A1, 1997 ;

189333-46-8 ~% 160133-32-4

文献：Leonardi, Amedeo; Barlocco, Daniela; Montesano, Federica; Cignarella, Giorgio; Motta, Gianni; Testa, Rodolfo; Poggesi, Elena; Seeber, Michele; De Benedetti, Pier G.; Fanelli, Francesca Journal of Medicinal Chemistry, 2004 , vol. 47, # 8 p. 1900 - 1918

64-17-5 769901-73-7 ~% 160133-32-4

文献：Leonardi, Amedeo; Barlocco, Daniela; Montesano, Federica; Cignarella, Giorgio; Motta, Gianni; Testa, Rodolfo; Poggesi, Elena; Seeber, Michele; De Benedetti, Pier G.; Fanelli, Francesca Journal of Medicinal Chemistry, 2004 , vol. 47, # 8 p. 1900 - 1918