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70891-37-1

70891-37-1结构式

常用中文名：Nafimidone
常用英文名：Nafimidone
CAS号：70891-37-1
分子式：C₁₅H₁₃ClN₂O
分子量：272.73000
发布时间：2016-04-05 10:09:50
更新时间：2024-01-11 18:04:36

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英文名	2-imidazol-1-yl-1-naphthalen-2-ylethanone,hydrochloride
英文别名	2-imidazol-1-yl-1-naphthalen-2-yl-ethanone hydrochloride 2-(1H-Imidazol-1-yl)-1-(2-naphthalenyl)ethanone monohydrochloride Nafimidone hydrochloride (USAN) Ethanone,2-(1H-imidazol-1-yl)-1-(2-naphthalenyl)-,monohydrochloride 2-(1-Imidazolylacetyl)naphthalene hydrochloride 2'-ACETONAPHTHONE,2-(1-IMIDAZOLYL)-,HYDROCHLORIDE Nafimidone HCl 1-(2-Naphthoylmethyl)imidazole hydrochloride 2-(1H-imidazol-1-yl)-1-(naphthalen-2-yl)ethanone hydrochloride Nafimidone hydrochloride

分子式	C₁₅H₁₃ClN₂O
分子量	272.73000
精确质量	272.07200
PSA	34.89000
LogP	3.72120

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KM5780880

CHEMICAL NAME :: Ethanone, 2-(1H-imidazol-1-yl)-1-(2-naphthalenyl)-, monohydrochloride

CAS REGISTRY NUMBER :: 70891-37-1

LAST UPDATED :: 199203

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C15-H12-N2-O.Cl-H

MOLECULAR WEIGHT :: 272.75

WISWESSER LINE NOTATION :: L66J BV1- AT5N CNJ &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 504 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 29,1577,1986

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 420 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 120,185,1981

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 210 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold

REFERENCE :: BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 120,185,1981

海关编码	2934999090

288-32-4结构式

288-32-4

613-54-7结构式

613-54-7

~38%

70891-37-1结构式

70891-37-1

文献：Roman, Gheorghe; Vlahakis, Jason Z.; Vukomanovic, Dragic; Nakatsu, Kanji; Szarek, Walter A. ChemMedChem, 2010 , vol. 5, # 9 p. 1541 - 1555

上游产品 2
288-32-4 613-54-7
下游产品 3
70891-42-8 70891-65-5 71009-17-1

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%