138680-08-7

• 常用中文名：(R)-佐匹克隆
• 常用英文名：[(7R)-6-(5-chloropyridin-2-yl)-5-oxo-7H-pyrrolo[3,4-b]pyrazin-7-yl] 4-methylpiperazine-1-carboxylate
• CAS号：138680-08-7
• 分子式：C₁₇H₁₇ClN₆O₃
• 分子量：388.80800
• 发布时间：2018-03-30 08:00:00
• 更新时间：2024-01-16 20:28:25

名称

• 中文名: (R)-佐匹克隆杂质
• 英文名: [(7R)-6-(5-chloropyridin-2-yl)-5-oxo-7H-pyrrolo[3,4-b]pyrazin-7-yl] 4-methylpiperazine-1-carboxylate
• 中文别名: (R)-佐匹克隆
• 英文别名: ZPC; R-(-)-zopiclone; Tocris-1094; Lopac-Z-4900; (R)-zolpiclone; (5R)-6-(5-chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl 4-methylpiperazine-1-carboxylate; Zopiclone,(R); (+)-6-(5-chloropyrid-2-yl)-5-(4-methylpiperazin-1-yl)carbonyloxy-7-oxo-6,7-dihydro-5H-pyrrolo[3-4-b]pyrazine; (-)-Zopiclone; (R)-6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo-[3,4-b] pyrazin-5-yl 4-methylpiperazine-1-carboxylate

物化性质

• 分子式: C₁₇H₁₇ClN₆O₃
• 分子量: 388.80800
• 精确质量: 388.10500
• PSA: 91.76000
• LogP: 1.50880

安全

• 危险品运输编码: NONH for all modes of transport

合成路线

1107971-11-8 ~99% 138680-08-7

文献：ESTEVE QUIMICA, S.A. Patent: EP2020403 A1, 2009 ; Location in patent: Page/Page column 8 ;

915038-31-2 ~83% 138680-08-7

文献：LEK Pharmaceuticals d.d. Patent: EP2345655 A1, 2011 ; Location in patent: Page/Page column 12 ;

144025-94-5 ~46% 138680-08-7

文献：USV LIMITED Patent: WO2009/63486 A2, 2009 ; Location in patent: Page/Page column 22 ;

138729-47-2 ~42% 138680-08-7

文献：LEK Pharmaceuticals d.d. Patent: EP2345655 A1, 2011 ; Location in patent: Page/Page column 14 ;

863393-46-8 ~% 138680-08-7

文献：Wessel, Thomas; Caron, Judy Patent: US2005/222156 A1, 2005 ; Location in patent: Page/Page column 3 ;

43200-80-2 ~24% 138680-08-7 138729-47-2

文献：LEK Pharmaceuticals d.d. Patent: EP2345655 A1, 2011 ; Location in patent: Page/Page column 12 ;

上下游产品

上游产品  4
1107971-11-8 138729-47-2 863393-46-8 43200-80-2
下游产品  3
43200-81-3 43200-80-2 138729-47-2