74733-29-2

• 常用中文名：2-氟-4-甲基苯甲酸甲酯
• 常用英文名：Methyl 2-fluoro-4-methylbenzoate
• CAS号：74733-29-2
• 分子式：C₉H₉FO₂
• 分子量：168.16500
• 发布时间：2018-03-02 08:00:00
• 更新时间：2024-01-09 08:41:12

名称

• 中文名: 2-氟-4-甲基苯甲酸甲酯
• 英文名: Methyl 2-fluoro-4-methylbenzoate
• 英文别名: 2-fluoro-4-methylbenzoic acid methyl ester; methyl-2-fluoro-4-methylbenzoate

物化性质

• 密度: 1.138g/cm3
• 沸点: 226.825ºC at 760 mmHg
• 分子式: C₉H₉FO₂
• 分子量: 168.16500
• 闪点: 88.537ºC
• 精确质量: 168.05900
• PSA: 26.30000
• LogP: 1.92070
• 折射率: 1.491
• 储存条件: 2-8°C

合成路线

67-56-1 7697-23-6 ~10% 74733-29-2

文献：PFIZER INC.; CAMERON, Kimberly O'Keefe; KRAUSS, Achim Hans-Peter; LEFKER, Bruce Allen; NAIR, Sajiv Krishnan; PRASANNA, Ganesh; RUI, Eugene Yuanjin Patent: WO2010/116270 A1, 2010 ; Location in patent: Page/Page column 55 ; WO 2010/116270 A1

74-88-4 7697-23-6 ~79% 74733-29-2

文献：Wang, Min; Davis, Toni; Gao, Mingzhang; Zheng, Qi-Huang Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 7 p. 1742 - 1747

67-56-1 59189-98-9 ~% 74733-29-2

文献：Yea, Christopher M.; Allan, Christine E.; Ashworth, Doreen M.; Barnett, James; Baxter, Andy J.; Broadbridge, Janice D.; Franklin, Richard J.; Hampton, Sally L.; Hudson, Peter; Horton, John A.; Jenkins, Paul D.; Penson, Andy M.; Pitt, Gary R. W.; Riviere, Pierre; Robson, Peter A.; Rooker, David P.; Semple, Graeme; Sheppard, Andy; Haigh, Robert M.; Roe, Michael B. Journal of Medicinal Chemistry, 2008 , vol. 51, # 24 p. 8124 - 8134

7697-23-6 ~75% 74733-29-2

文献：Ashworth, Doreen; Pitt, Gary R W; Hudson, Peter; Yea, Christopher; Franklin, Richard J; Semple, Graeme; Jenkins, David Paul Patent: US2004/38962 A1, 2004 ;