26510-52-1

• 常用中文名：皮考林乙酸乙酯
• 常用英文名：Ethyl 3-oxo-3-(2-pyridinyl)propanoate
• CAS号：26510-52-1
• 分子式：C₁₀H₁₁NO₃
• 分子量：193.199
• 相关类别： 有机原料 羧酸类化合物及衍生物 羧酸酯及其衍生物
• 发布时间：2018-05-18 08:00:00
• 更新时间：2024-01-08 12:05:59
• 下载msds

名称

• 中文名: 皮考林乙酸乙酯
• 英文名: ethyl 3-oxo-3-pyridin-2-ylpropanoate
• 中文别名: 3-氧代-3-(吡啶-2-基)丙酸乙酯; 吡啶甲酰乙酸乙酯
• 英文别名: Ethyl 3-(2-pyridyl)-3-oxopropionate; Ethyl 3-oxo-3-(2-pyridinyl)propanoate; ethyl 3-oxo-(2-pyridinyl)propanoate; 3-oxo-3-pyridin-2-ylpropionic acid ethyl ester; ethyl 3-oxo-3-(pyridin-2-yl)propanoate; 3-oxo-3-(2-pyridyl)-propanoic acid ethyl ester; ethyl 3-oxo-3-(2-pyridyl)propionate; MFCD00094022; 2-Pyridinepropanoic acid, β-oxo-, ethyl ester; Ethyl picolinoylacetate; ethyl 3-oxo-3-(2-pyridyl)propanoate; ethyl 3-(2-pyridyl)-3-oxopropanoate

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 276.6±15.0 °C at 760 mmHg
• 分子式: C₁₀H₁₁NO₃
• 分子量: 193.199
• 闪点: 121.1±20.4 °C
• 精确质量: 193.073898
• PSA: 56.26000
• LogP: 1.08
• 外观性状: 透明稻黄色至棕色液体
• 蒸汽压: 0.0±0.6 mmHg at 25°C
• 折射率: 1.511
• 储存条件:

  密闭于阴凉干燥环境中

• 稳定性:

  遵照规定使用和储存则不会分解。

• 分子结构:

  1、 摩尔折射率：50.04

  2、 摩尔体积（m³/mol）：167.1

  3、 等张比容（90.2K）：430.6

  4、 表面张力（dyne/cm）：44.0

  5、 极化率（10 ^-24cm ³）：19.83

• 计算化学:

  1.疏水参数计算参考值（XlogP）:1.3

  2.氢键供体数量:0

  3.氢键受体数量:4

  4.可旋转化学键数量:5

  5.互变异构体数量:3

  6.拓扑分子极性表面积56.3

  7.重原子数量:14

  8.表面电荷:0

  9.复杂度:215

  10.同位素原子数量:0

  11.确定原子立构中心数量:0

  12.不确定原子立构中心数量:0

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:1

• 更多:

  1. 性状：无可用

  2. 密度（g/mL,25/4℃）：1.164

  3. 相对蒸汽密度（g/mL,空气=1）：无可用

  4. 熔点（ºC）：无可用

  5. 沸点（ºC,常压）：100-104

  6. 沸点（ºC,5.2kPa）：无可用

  7. 折射率：1.516-1.519

  8. 闪点（ºC）：无可用

  9. 比旋光度（º）：无可用

  10. 自燃点或引燃温度（ºC）：无可用

  11. 蒸气压（kPa,25ºC）：无可用

  12. 饱和蒸气压（kPa,60ºC）：无可用

  13. 燃烧热（KJ/mol）：无可用

  14. 临界温度（ºC）：无可用

  15. 临界压力（KPa）：无可用

  16. 油水（辛醇/水）分配系数的对数值：无可用

  17. 爆炸上限（%,V/V）：无可用

  18. 爆炸下限（%,V/V）：无可用

  19. 溶解性：无可用

MSDS

Name: Ethyl Picolinoylacetate Material Safety Data Sheet Synonym: None CAS: 26510-52-1 Section 1 - Chemical Product MSDS Name:Ethyl Picolinoylacetate Material Safety Data Sheet Synonym:None Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 26510-52-1 Ethylpicolinoyl Acetate 100 % unlisted Hazard Symbols: None Listed. Risk Phrases: None Listed. Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW The toxicological properties of this material have not been fully investigated. Potential Health Effects Eye: May cause eye irritation. Skin: May cause skin irritation. The toxicological properties of this material have not been fully investigated. Ingestion: Ingestion of large amounts may cause gastrointestinal irritation. The toxicological properties of this substance have not been fully investigated. Inhalation: May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. Chronic: No information found. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Ingestion: Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid if irritation or symptoms occur. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas. Containers may explode when heated. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Use agent most appropriate to extinguish fire. Cool containers with flooding quantities of water until well after fire is out. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Remove all sources of ignition. Provide ventilation. Section 7 - HANDLING and STORAGE Handling: Wash hands before eating. Use only in a well-ventilated area. Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Do not get on skin or in eyes. Avoid ingestion and inhalation. Wash clothing before reuse. Storage: Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Good general ventilation should be sufficient to control airborne levels. Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Exposure Limits CAS# 26510-52-1: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Liquid Color: clear almost colorless Odor: Moderate pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: 100 - 104 deg C @ .30mm Hg Freezing/Melting Point: Not available. Autoignition Temperature: Not available. Flash Point: > 200 deg C (> 392.00 deg F) Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: neglegible in water Specific Gravity/Density: Molecular Formula: Molecular Weight: 193.20 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Stable under normal temperatures and pressures. Conditions to Avoid: High temperatures, excess heat. Incompatibilities with Other Materials: Strong oxidizing agents, acids, bases. Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide. Hazardous Polymerization: Will not occur. Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 26510-52-1 unlisted. LD50/LC50: Not available. Carcinogenicity: Ethylpicolinoyl Acetate - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Not regulated as a hazardous material. IMO Not regulated as a hazardous material. RID/ADR Not regulated as a hazardous material. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: Not available. Risk Phrases: Safety Phrases: S 24/25 Avoid contact with skin and eyes. WGK (Water Danger/Protection) CAS# 26510-52-1: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 26510-52-1 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 26510-52-1 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A

毒性和生态

生态学数据: 通常对水是不危害的，若无政府许可，勿将材料排入周围环境。

安全

• 危害码 (欧洲): Xi
• 风险声明 (欧洲): 36
• 安全声明 (欧洲): S24/25
• 海关编码: 2933399090

海关

海关编码	2933399090
中文概述	2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%