31865-25-5

• 常用中文名：3-CBZ-6-氧杂-3-氮杂二环[3.1.0]己烷
• 常用英文名：3-Cbz-6-oxa-3-aza-bicyclo[3.1.0]hexane
• CAS号：31865-25-5
• 分子式：C₁₂H₁₃NO₃
• 分子量：219.236
• 发布时间：2016-09-02 01:36:08
• 更新时间：2024-01-06 20:12:01

名称

• 中文名: 3-CBZ-6-氧杂-3-氮杂二环[3.1.0]己烷
• 英文名: benzyl 6-oxa-3-azabicyclo[3.1.0]hexane-3-carboxylate
• 中文别名: 3-氮杂-6-氧杂双环[3.1]己烷-3-羧酸苄酯
• 英文别名: 1-benzyloxycarbonyl-3,4-epoxypyrrolidine; 3-Cbz-6-oxa-3-aza-bicyclo[3.1.0]hexane; 3,4-epoxy-1-carbobenzyloxy-pyrrolidine; Benzyl 6-oxa-3-azabicyclo[3.1.0]hexane-3-carboxylate; 6-Oxa-3-azabicyclo[3.1.0]hexane-3-carboxylic acid, phenylmethyl ester; N-benzyloxycarbonyl-3,4-epoxy-pyrrolidine; 3-Aza-6-oxabicyclo[3.1]hexane-3-carboxylic acid benzyl ester

物化性质

• 密度: 1.305±0.06 g/cm3
• 沸点: 353.9±42.0 °C at 760 mmHg
• 分子式: C₁₂H₁₃NO₃
• 分子量: 219.236
• 闪点: 167.8±27.9 °C
• 精确质量: 219.089539
• PSA: 42.07000
• LogP: 1.32
• 外观性状: 白色至黄色固体
• 蒸汽压: 0.0±0.8 mmHg at 25°C
• 折射率: 1.596
• 储存条件: 2-8°C，干燥
• 水溶解性: Very slightly soluble (0.48 g/L) (25 ºC)

安全

• 危害码 (欧洲): Xi
• 海关编码: 2934999090

合成路线

31970-04-4 ~99% 31865-25-5

文献：Pfizer Inc Patent: US2005/256310 A1, 2005 ; Location in patent: Page/Page column 12 ;

31970-04-4 937-14-4 ~95% 31865-25-5

文献：NYCOMED GMBH; BARTELS, Bjoern; WEINBRENNER, Steffen; MARX, Degenhard; DIEFENBACH, Joerg; DUNKERN, Torsten; MENGE, Wiro M.P.B.; CHRISTIAANS, Johannes A. M. Patent: WO2010/15588 A1, 2010 ; Location in patent: Page/Page column 94 ; WO 2010/015588 A1

25070-76-2 ~% 31865-25-5

文献：Kamal, Ahmed; Shaik, Ahmad Ali; Sandbhor, Mahendra; Malik, M. Shaheer; Kaga, Harumi Tetrahedron Letters, 2004 , vol. 45, # 43 p. 8057 - 8059

501-53-1 ~% 31865-25-5

文献：Kamal, Ahmed; Shaik, Ahmad Ali; Sandbhor, Mahendra; Malik, M. Shaheer; Kaga, Harumi Tetrahedron Letters, 2004 , vol. 45, # 43 p. 8057 - 8059

13139-17-8 ~% 31865-25-5

文献：NOVARTIS AG; BARSANTI, Paul, A.; HU, Cheng; JIN, Xianming; NG, Simon, C.; PFISTER, Keith, B.; SENDZIK, Martin; SUTTON, James Patent: WO2012/101064 A1, 2012 ; WO 2012/101064 A1

上下游产品

上游产品  5
31970-04-4 937-14-4 25070-76-2 501-53-1
13139-17-8
下游产品  3
285-68-7 163439-83-6 596793-30-5

海关

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%