51070-56-5

• 常用中文名：(1,1-二氧代四氢-1-lambda*6*-噻吩-3-氨基)乙酸
• 常用英文名：JFD01307SC
• CAS号：51070-56-5
• 分子式：C₆H₁₁NO₄S
• 分子量：193.22100
• 相关类别： 信号通路 抗感染 细菌
• 发布时间：2018-12-28 22:06:42
• 更新时间：2024-01-08 17:40:49
• JFD01307SC是谷氨酰胺合成酶抑制剂和抗结核药物。JFD01307SC作为L-谷氨酸盐的模拟物,因此是参与谷氨酰胺生物合成的靶酶。

名称

• 中文名: (1,1-二氧代四氢-1-lambda*6*-噻吩-3-氨基)乙酸
• 英文名: 2-[(1,1-dioxothiolan-3-yl)amino]acetic acid
• 英文别名: N-(Tetrahydro-1,1-dioxido-3-thienyl)-glycine; N-(1,1-dioxidotetrahydrothiophen-3-yl)glycine; HMS548G19

物化性质

• 熔点: 268-270℃
• 分子式: C₆H₁₁NO₄S
• 分子量: 193.22100
• 精确质量: 193.04100
• PSA: 91.85000
• LogP: 0.31940
• 外观性状: 固体
• 储存条件: 2-8°C，密封，干燥

生物活性

• 描述: JFD01307SC是谷氨酰胺合成酶抑制剂和抗结核药物。JFD01307SC作为L-谷氨酸盐的模拟物,因此是参与谷氨酰胺生物合成的靶酶。
• 相关类别:
  信号通路 >> 抗感染 >> 细菌

MSDS

Name: 2-[(1 1-Dioxotetrahydro-1h-1lambda~6~-thiophen-3-yl)amino]acetic Material Safety Data Sheet Synonym: 3-(Carboxymethylamino)thiolane-1,1-dioxid CAS: 51070-56-5 Section 1 - Chemical Product MSDS Name:2-[(1 1-Dioxotetrahydro-1h-1lambda~6~-thiophen-3-yl)amino]acetic Material Safety Data Sheet Synonym:3-(Carboxymethylamino)thiolane-1,1-dioxid Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 51070-56-5 2-[(1,1-Dioxotetrahydro-1H-1lambda~6~- 97% unlisted Hazard Symbols: XN Risk Phrases: 20/21/22 36/37/38 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Harmful by inhalation, in contact with skin and if swallowed. Irritating to eyes, respiratory system and skin. Potential Health Effects Eye: Causes eye irritation. Skin: Causes skin irritation. Harmful if absorbed through the skin. Ingestion: Harmful if swallowed. May cause irritation of the digestive tract. Inhalation: Harmful if inhaled. Causes respiratory tract irritation. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Get medical aid. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Section 7 - HANDLING and STORAGE Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Storage: Store in a cool, dry place. Store in a tightly closed container. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 51070-56-5: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Solid Color: white Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 268 - 270 deg C Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C6H11NO4S Molecular Weight: 193 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Not available. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Oxidizing agents, bases, acid chlorides. Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, oxides of sulfur, carbon dioxide, acrid smoke and fumes. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 51070-56-5 unlisted. LD50/LC50: Not available. Carcinogenicity: 2-[(1,1-Dioxotetrahydro-1H-1lambda~6~-thiophen-3-yl)amino]acetic acid - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Shipping Name: TOXIC SOLID, ORGANIC, N.O.S.* Hazard Class: 6.1 UN Number: 2811 Packing Group: III IMO Shipping Name: TOXIC SOLID, ORGANIC, N.O.S. Hazard Class: 6.1 UN Number: 2811 Packing Group: III RID/ADR Shipping Name: TOXIC SOLID, ORGANIC, N.O.S. Hazard Class: 6.1 UN Number: 2811 Packing group: III Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XN Risk Phrases: R 20/21/22 Harmful by inhalation, in contact with skin and if swallowed. R 36/37/38 Irritating to eyes, respiratory system and skin. Safety Phrases: S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36/37/39 Wear suitable protective clothing, gloves and eye/face protection. WGK (Water Danger/Protection) CAS# 51070-56-5: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 51070-56-5 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 51070-56-5 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A

安全

• 危险品运输编码: NONH for all modes of transport
• 海关编码: 2934999090

海关

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%