CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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CV6292000
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CHEMICAL NAME :
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Benzamidine, p-(methylsulfonyl)-, hydrochloride
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CAS REGISTRY NUMBER :
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5434-06-0
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LAST UPDATED :
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198806
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DATA ITEMS CITED :
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3
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MOLECULAR FORMULA :
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C8-H10-N2-O2-S.Cl-H
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MOLECULAR WEIGHT :
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234.72
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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1200 mg/kg
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TOXIC EFFECTS :
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Behavioral - convulsions or effect on seizure threshold Vascular - BP lowering not characterized in autonomic section Lungs, Thorax, or Respiration - cyanosis
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REFERENCE :
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JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 84,160,1945
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TYPE OF TEST :
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LDLo - Lowest published lethal dose
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ROUTE OF EXPOSURE :
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Intramuscular
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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1500 mg/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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REFERENCE :
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LANCAO Lancet. (7 Adam St., London WC2N 6AD, UK) V.1- 1823- Volume(issue)/page/year: 2,523,1944
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TYPE OF TEST :
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LDLo - Lowest published lethal dose
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ROUTE OF EXPOSURE :
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Intravenous
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SPECIES OBSERVED :
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Mammal - cat
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DOSE/DURATION :
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280 mg/kg
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TOXIC EFFECTS :
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Vascular - BP lowering not characterized in autonomic section
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REFERENCE :
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JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 84,160,1945
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