59865-16-6

• 常用中文名：异构环孢菌素A
• 常用英文名：Isocyclosporin A
• CAS号：59865-16-6
• 分子式：C₆₂H₁₁₁N₁₁O₁₂
• 分子量：1202.611
• 发布时间：2018-09-24 23:22:23
• 更新时间：2024-01-19 19:01:25
• Isocyclosporin A is a rearranged degradation product formed by acid treatment of cyclosporin A under aqueous and non-aqueous conditions.

名称

• 中文名: 异构环孢菌素A
• 英文名: Iso Cyclosporin A
• 中文别名: 异环胞素 A
• 英文别名: (2S,3R,4R,6E)-3-Hydroxy-4-Methyl-2-(MethylaMino)-6-octenoyl-(2S)-2-aMinobutanoyl-N-Methylglycyl-N-Methyl-L-leucyl-L-valyl-N-Methyl-L-leucyl-L-alanyl-D-alanyl-N-Methyl-L-leucyl-N-Methyl-L-leucyl-N-Methyl-L-valine (111)-Lactone; 30-Ethyl-34-[(4Z)-4-hexen-2-yl]-6,9,18,24-tetraisobutyl-3,21-diisopropyl-4,7,10,12,15,19,25,28-octamethyl-33-(methylamino)-1-oxa-4,7,10,13,16,19,22,25,28,31-decaazacyclotetratriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone; 1-Oxa-4,7,10,13,16,19,22,25,28,31-decaazacyclotetratriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone, 30-ethyl-4,7,10,12,15,19,25,28-octamethyl-33-(methylamino)-3,21-bis(1-methylethyl)-34-[(3Z)-1-methyl-3-penten-1-yl]-6,9,18,24-tetrakis(2-methylpropyl)-; Cyclo[L-Abu-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-[(3R,4R)-3-hydroxy*-N-methyl-5-[(E)-1-propenyl]-L-Leu-]]; isocyclosporin A; 30-ethyl-34-[(Z)-hex-4-en-2-yl]-4,7,10,12,15,19,25,28-octamethyl-33-me thylamino-6,9,18,24-tetrakis(2-methylpropyl)-3,21-dipropan-2-yl-1-oxa-4,7,10,13,16,19,22,25,28,31-decazacyclotetratriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone; Cyclosporin Impurity 9

物化性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 1280.5±65.0 °C at 760 mmHg
• 熔点: 148-152ºC
• 分子式: C₆₂H₁₁₁N₁₁O₁₂
• 分子量: 1202.611
• 闪点: 728.2±34.3 °C
• 精确质量: 1201.841309
• PSA: 276.59000
• LogP: 3.23
• 蒸汽压: 0.0±0.3 mmHg at 25°C
• 折射率: 1.538
• 储存条件: -20°C，密闭，干燥