5436-89-5

• 常用中文名：1-(4-propanoylpiperazin-1-yl)propan-1-one
• 常用英文名：1-(4-propanoylpiperazin-1-yl)propan-1-one
• CAS号：5436-89-5
• 分子式：C₁₀H₁₈N₂O₂
• 分子量：198.26200
• 发布时间：2017-10-01 12:34:59
• 更新时间：2024-01-10 11:42:31

名称

• 英文名: N,N'-dipropionyl piperazine
• 英文别名: 1,4-Dipropionylpiperazine

物化性质

• 密度: 1.076g/cm3
• 沸点: 384.2ºC at 760 mmHg
• 分子式: C₁₀H₁₈N₂O₂
• 分子量: 198.26200
• 闪点: 179ºC
• 精确质量: 198.13700
• PSA: 40.62000
• LogP: 0.35300
• 折射率: 1.49

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : TL6780000 CHEMICAL NAME : Piperazine, 1,4-dipropionyl- CAS REGISTRY NUMBER : 5436-89-5 BEILSTEIN REFERENCE NO. : 1571602 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C10-H18-N2-O2 MOLECULAR WEIGHT : 198.30 WISWESSER LINE NOTATION : T6N DNTJ AV2 DV2 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1750 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 11,801,1968

合成路线

76816-54-1 79-03-8 ~73% 5436-89-5

文献：Martini, Elisabetta; Salvicchi, Alberto; Ghelardini, Carla; Manetti, Dina; Dei, Silvia; Guandalini, Luca; Martelli, Cecilia; Melchiorre, Michele; Cellai, Cristina; Scapecchi, Serena; Teodori, Elisabetta; Romanelli, Maria Novella Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 21 p. 7606 - 7614

110-85-0 54509-73-8 ~% 76816-54-1 5436-89-5

文献：Texaco Inc. Patent: US4866177 A1, 1989 ;

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