34451-66-6

• 常用中文名：2-乙基-2-羟基丁腈
• 常用英文名：2-ethyl-2-hydroxybutyronitrile
• CAS号：34451-66-6
• 分子式：C₆H₁₁NO
• 分子量：113.15800
• 发布时间：2018-08-05 17:25:24
• 更新时间：2024-01-03 12:54:08

名称

• 中文名: 2-乙基-2-羟基丁腈
• 英文名: 2-ethyl-2-hydroxybutanenitrile
• 英文别名: 2-Aethyl-2-hydroxy-butyronitril; BUTYRONITRILE,2-ETHYL-2-HYDROXY; 2-Ethyl-2-hydroxybutyronitrile; EINECS 252-037-9; Propioncyanhydrin; 3-Pentanone cyanohydrin; Diaethylketon-cyanhydrin

物化性质

• 密度: 0.954g/cm3
• 沸点: 214.4ºC at 760 mmHg
• 分子式: C₆H₁₁NO
• 分子量: 113.15800
• 闪点: 83.5ºC
• 精确质量: 113.08400
• PSA: 44.02000
• LogP: 1.06108
• 折射率: 1.44
• 储存条件: 室温

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : ET9950000 CHEMICAL NAME : Butyronitrile, 2-ethyl-2-hydroxy- CAS REGISTRY NUMBER : 34451-66-6 BEILSTEIN REFERENCE NO. : 1700508 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C6-H11-N-O MOLECULAR WEIGHT : 113.18 WISWESSER LINE NOTATION : QX2&2&CN HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689

合成路线

143-33-9 96-22-0 ~2% 34451-66-6

文献：Bristol-Myers Squibb Company Patent: US2008/4265 A1, 2008 ; Location in patent: Page/Page column 15 ;

7677-24-9 96-22-0 ~% 34451-66-6

文献：De Castro, Sonia; Garcia-Aparicio, Carlos; Andrei, Graciela; Snoeck, Robert; Balzarini, Jan; Camarasa, Maria-Jose; Velazquez, Sonsoles Journal of Medicinal Chemistry, 2009 , vol. 52, # 6 p. 1582 - 1591

151-50-8 96-22-0 ~% 34451-66-6

文献：Sutin, Lori; Andersson, Soeren; Bergquist, Lars; Castro, Victor M.; Danielsson, Eva; James, Stephen; Henriksson, Martin; Johansson, Lars; Kaiser, Christina; Flyren, Katarina; Williams, Meredith Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 17 p. 4837 - 4840

74-90-8 96-22-0 ~% 34451-66-6

文献：Ultee Recueil des Travaux Chimiques des Pays-Bas, 1909 , vol. 28, p. 11 Chemische Berichte, 1906 , vol. 39, p. 1858

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