612069-27-9

• 常用中文名：N',N'-二(去甲基)阿奇霉素
• 常用英文名：3'-N,N-Di(desmethyl) Azithromycin
• CAS号：612069-27-9
• 分子式：C₃₆H₆₈N₂O₁₂
• 分子量：720.931
• 发布时间：2018-08-11 15:28:51
• 更新时间：2024-01-22 18:27:26

名称

• 中文名: 阿奇霉素杂质 E
• 英文名: 3'-N,N-Di(desmethyl) Azithromycin
• 英文别名: 1-Oxa-6-azacyclopentadecan-15-one, 11-[(3-amino-3,4,6-trideoxy-β-D-xylo-hexopyranosyl)oxy]-13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,1 0,12,14-heptamethyl-, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-; (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-[(2S,3R,4S,6R)-4-amino-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-3,4,10-trihydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one; (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-[(3-Amino-3,4,6-trideoxy-β-D-xylo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideo xy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranoside; Azithromycin Impurity 5

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 817.3±65.0 °C at 760 mmHg
• 分子式: C₃₆H₆₈N₂O₁₂
• 分子量: 720.931
• 闪点: 448.1±34.3 °C
• 精确质量: 720.477234
• PSA: 202.86000
• LogP: 2.62
• 蒸汽压: 0.0±0.6 mmHg at 25°C
• 折射率: 1.542

合成路线

172617-84-4 ~80% 612069-27-9

文献：Jakopovic, Ivana Palej; Krajacic, Mirjana Bukvic; Skugor, Maja Matanovic; Stimac, Vlado; Pesic, Dijana; Vujasinovic, Ines; Alihodzic, Sulejman; Paljetak, Hana Cipcic; Kragol, Goran Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 10 p. 3527 - 3530

83905-01-5 ~% 612069-27-9

文献：Jakopovic, Ivana Palej; Krajacic, Mirjana Bukvic; Skugor, Maja Matanovic; Stimac, Vlado; Pesic, Dijana; Vujasinovic, Ines; Alihodzic, Sulejman; Paljetak, Hana Cipcic; Kragol, Goran Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 10 p. 3527 - 3530

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