108828-56-4

• 常用中文名：3-carbamyl-(3'-picolyl)-4-methoxy-1-benzamide
• 常用英文名：3-carbamyl-(3'-picolyl)-4-methoxy-1-benzamide
• CAS号：108828-56-4
• 分子式：C₁₅H₁₅N₃O₃
• 分子量：285.29800
• 发布时间：2017-06-29 14:34:54
• 更新时间：2024-03-06 20:21:28

名称

• 英文名: 4-methoxy-3-N-(pyridin-3-ylmethyl)benzene-1,3-dicarboxamide
• 英文别名: 3-Carbamyl-(3'-picolyl)-4-methoxy-1-benzamide; 4-Methoxy-N(sup 3)-(3-pyridinylmethyl)-1,3-benzenedicarboxamide; 4-methoxy-N3-(pyridin-3-ylmethyl)benzene-1,3-dicarboxamide; 1,3-Benzenedicarboxamide,4-methoxy-N3-(3-pyridinylmethyl); G 619; 1,3-Benzenedicarboxamide,4-methoxy-N(sup 3)-(3-pyridinylmethyl)

物化性质

• 密度: 1.26g/cm3
• 沸点: 537.9ºC at 760mmHg
• 分子式: C₁₅H₁₅N₃O₃
• 分子量: 285.29800
• 闪点: 279.1ºC
• 精确质量: 285.11100
• PSA: 98.79000
• LogP: 2.57810
• 蒸汽压: 1.21E-11mmHg at 25°C
• 折射率: 1.605

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : CZ2268500 CHEMICAL NAME : 1,3-Benzenedicarboxamide, 4-methoxy-N(sup 3)-(3-pyridinylmethyl)- CAS REGISTRY NUMBER : 108828-56-4 LAST UPDATED : 199512 DATA ITEMS CITED : 6 MOLECULAR FORMULA : C15-H15-N3-O3 MOLECULAR WEIGHT : 285.33 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1725 mg/kg TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - lacrimation Behavioral - ataxia Nutritional and Gross Metabolic - body temperature decrease REFERENCE : CDREEA Cardiovascular Drug Reviews. (Raven Press, 1185 Avenue of the Americas, New York, NY 10036) V.6- 1988- Volume(issue)/page/year: 11,116,1993 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1326 mg/kg TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - lacrimation Behavioral - ataxia Nutritional and Gross Metabolic - body temperature decrease REFERENCE : CDREEA Cardiovascular Drug Reviews. (Raven Press, 1185 Avenue of the Americas, New York, NY 10036) V.6- 1988- Volume(issue)/page/year: 11,116,1993 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 569 mg/kg TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - lacrimation Behavioral - ataxia Nutritional and Gross Metabolic - body temperature decrease REFERENCE : CDREEA Cardiovascular Drug Reviews. (Raven Press, 1185 Avenue of the Americas, New York, NY 10036) V.6- 1988- Volume(issue)/page/year: 11,116,1993 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1758 mg/kg TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - lacrimation Behavioral - ataxia Nutritional and Gross Metabolic - body temperature decrease REFERENCE : CDREEA Cardiovascular Drug Reviews. (Raven Press, 1185 Avenue of the Americas, New York, NY 10036) V.6- 1988- Volume(issue)/page/year: 11,116,1993 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 966 mg/kg TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - lacrimation Behavioral - ataxia Nutritional and Gross Metabolic - body temperature decrease REFERENCE : CDREEA Cardiovascular Drug Reviews. (Raven Press, 1185 Avenue of the Americas, New York, NY 10036) V.6- 1988- Volume(issue)/page/year: 11,116,1993 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 463 mg/kg TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - lacrimation Behavioral - ataxia Nutritional and Gross Metabolic - body temperature decrease REFERENCE : CDREEA Cardiovascular Drug Reviews. (Raven Press, 1185 Avenue of the Americas, New York, NY 10036) V.6- 1988- Volume(issue)/page/year: 11,116,1993