192726-05-9

• 常用中文名：(S)-N-[(2S,4S,5S)-5-Amino-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)butanamide
• 常用英文名：(S)-N-[(2S,4S,5S)-5-Amino-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)butanamide
• CAS号：192726-05-9
• 分子式：C₂₇H₃₈N₄O₃
• 分子量：466.61600
• 发布时间：2017-06-02 21:48:39
• 更新时间：2024-01-09 12:24:56

名称

• 英文名: (2S)-N-[(2S,4S,5S)-5-amino-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanamide
• 英文别名: (2S,3S,5S)-2-amino-3-hydroxy-5-(2S-(2-oxotetrahydropyrimidin-2-yl)-3-methylbutanoyl)amino-1,6-diphenylhexane; (2S)-N-[(2S,4S,5S)-5-amino-4-hydroxy-1,6-diphenylhexane-2-yl]-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanamide; (S)-N-[(2S,4S,5S)-5-AMINO-4-HYDROXY-1,6-DIPHENYLHEXAN-2-YL]-3-METHYL-2-(2-OXOTETRAHYDROPYRIMIDIN-1(2H)-YL)BUTANAMIDE; (|AS)-N-[(1S,3S,4S)-4-Amino-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-|A-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetamide; (2S,3S,5S)-2-amino-3-hydroxy-5-(2S-(1-tetrahydro-pyrimid-2-onyl)-3-methylbutanoyl)amino-1,6-diphenylhexane

物化性质

• 密度: 1.154g/cm3
• 沸点: 762.223ºC at 760 mmHg
• 分子式: C₂₇H₃₈N₄O₃
• 分子量: 466.61600
• 闪点: 414.778ºC
• 精确质量: 466.29400
• PSA: 114.67000
• LogP: 3.59330
• 外观性状: 白色固体
• 蒸汽压: 0mmHg at 25°C
• 折射率: 1.577

合成路线

192726-04-8 ~% 192726-05-9

文献：Abbott Laboratories Patent: EP1170289 A2, 2002 ; Location in patent: Page 65 ;

192800-77-4 ~% 192726-05-9

文献：Reddy, G. S. Kiran Kumar; Ali, Akbar; Nalam, Madhavi N. L.; Anjum, Saima Ghafoor; Cao, Hong; Nathans, Robin S.; Schiffer, Celia A.; Rana, Tariq M. Journal of Medicinal Chemistry, 2007 , vol. 50, # 18 p. 4316 - 4328

192725-50-1 ~% 192726-05-9

文献：Reddy, G. S. Kiran Kumar; Ali, Akbar; Nalam, Madhavi N. L.; Anjum, Saima Ghafoor; Cao, Hong; Nathans, Robin S.; Schiffer, Celia A.; Rana, Tariq M. Journal of Medicinal Chemistry, 2007 , vol. 50, # 18 p. 4316 - 4328

156732-15-9 ~% 192726-05-9

文献：Reddy, G. S. Kiran Kumar; Ali, Akbar; Nalam, Madhavi N. L.; Anjum, Saima Ghafoor; Cao, Hong; Nathans, Robin S.; Schiffer, Celia A.; Rana, Tariq M. Journal of Medicinal Chemistry, 2007 , vol. 50, # 18 p. 4316 - 4328

402712-50-9 156732-15-9 ~% 192726-05-9

文献：Abbott Laboratories Patent: US6372905 B1, 2002 ; Location in patent: Example 3 ;