10167-97-2

• 常用中文名：2-氨基-5-甲氧基吡啶
• 常用英文名：2-Amino-5-methoxypyridine
• CAS号：10167-97-2
• 分子式：C₆H₈N₂O
• 分子量：124.141
• 相关类别： 医药中间体 杂环化合物 吡啶类化合物 吡啶衍生物
• 发布时间：2018-09-19 13:52:52
• 更新时间：2024-01-05 07:59:42

名称

• 中文名: 2-氨基-5-甲氧基吡啶
• 英文名: 2-Amino-5-methoxypyridine
• 中文别名: 5-甲氧基吡啶-2-胺; 5-甲氧基-2-氨基吡啶
• 英文别名: 5-Methoxy-Pyridin-2-Ylamine; 5-Methoxypyridin-2-amine

物化性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 251.6±20.0 °C at 760 mmHg
• 分子式: C₆H₈N₂O
• 分子量: 124.141
• 闪点: 106.0±21.8 °C
• 精确质量: 124.063660
• PSA: 48.14000
• LogP: 0.86
• 外观性状: 暗红色油状
• 蒸汽压: 0.0±0.5 mmHg at 25°C
• 折射率: 1.561
• 储存条件: -20°C Freezer, Under Inert Atmosphere

MSDS

Material Safety Data Sheet Section1. Identification of the substance Product Name: 5-Methoxypyridin-2-amine Synonyms: Section2. Hazards identification Harmful by inhalation, in contact with skin, and if swallowed. Section3. Composition/information on ingredients. Ingredient name:5-Methoxypyridin-2-amine CAS number:10167-97-2 Section4. First aid measures Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing contaminated clothing and shoes. If irritation persists, seek medical attention. Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical attention. Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention. Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention. Section5. Fire fighting measures In the event of a fire involving this material, alone or in combination with other materials, use dry powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus should be worn. Section6. Accidental release measures Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national standards. Respiratory precaution:Wear approved mask/respirator Hand precaution:Wear suitable gloves/gauntlets Skin protection:Wear suitable protective clothing Eye protection:Wear suitable eye protection Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container for disposal. See section 12. Environmental precautions: Do not allow material to enter drains or water courses. Section7. Handling and storage Handling:This product should be handled only by, or under the close supervision of, those properly qualified in the handling and use of potentially hazardous chemicals, who should take into account the fire, health and chemical hazard data given on this sheet. Store in closed vessels. Storage: Section8. Exposure Controls / Personal protection Engineering Controls: Use only in a chemical fume hood. Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles. General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse. Section9. Physical and chemical properties Appearance:Not specified Boiling point:No data No data Melting point: Flash point:No data Density:No data Molecular formula:C6H8N2O Molecular weight:124.1 Section10. Stability and reactivity Conditions to avoid: Heat, flames and sparks. Materials to avoid: Oxidizing agents. Possible hazardous combustion products: Carbon monoxide, nitrogen oxides. Section11. Toxicological information No data. Section12. Ecological information No data. Section13. Disposal consideration Arrange disposal as special waste, by licensed disposal company, in consultation with local waste disposal authority, in accordance with national and regional regulations. Section14. Transportation information Non-harzardous for air and ground transportation. Section15. Regulatory information No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302, or have known CAS numbers that exceed the threshold reporting levels established by SARA Title III, Section 313. SECTION 16 - ADDITIONAL INFORMATION N/A

安全

• 海关编码: 2933399090

合成路线

76066-07-4 ~93% 10167-97-2

文献：BIOLIPOX AB Patent: WO2007/51982 A1, 2007 ; Location in patent: Page/Page column 49 ;

638352-78-0 ~99% 10167-97-2

文献：Tibotec Pharmaceuticals Ltd. Patent: WO2007/113290 A1, 2007 ; Location in patent: Page/Page column 40-42 ;

1072-97-5 124-41-4 ~44% 10167-97-2

文献：Van De Poel, Herve; Guillaumet, Gerald; Viaud-Massuard, Marie-Claude Heterocycles, 2002 , vol. 57, # 1 p. 55 - 71

20511-12-0 124-41-4 ~30% 10167-97-2

文献：MYRIAD GENETICS, INC.; CYTOVIA, INC. Patent: WO2005/3100 A2, 2005 ; Location in patent: Page 231 ; WO 2005/003100 A2

24100-18-3 ~% 10167-97-2

文献：Pharmazie, , vol. 55, # 12 p. 907 - 912

20511-12-0 12775-96-1 ~% 10167-97-2

文献：US3984549 A1, ;

105170-27-2 ~66% 10167-97-2

文献：Fantasia, Serena; Windisch, Johannes; Scalone, Michelangelo Advanced Synthesis and Catalysis, 2013 , vol. 355, # 4 p. 627 - 631

20511-12-0 67-56-1 ~52% 10167-97-2

文献：Trapani, Giuseppe; Franco, Massimo; Ricciardi, Laura; Latrofa, Andrea; Genchi, Giuseppe; Sanna, Enrico; Tuveri, Francesca; Cagetti, Elisabetta; Biggio, Giovanni; Liso, Gaetano Journal of Medicinal Chemistry, 1997 , vol. 40, # 19 p. 3109 - 3118

477889-91-1 ~% 10167-97-2

文献：European Journal of Organic Chemistry, , # 20 p. 3948 - 3957

上下游产品

上游产品  9
76066-07-4 638352-78-0 1072-97-5 124-41-4
20511-12-0 24100-18-3 105170-27-2 67-56-1
477889-91-1
下游产品  9
55717-46-9 105170-27-2 1092394-15-4 139585-48-1
325796-84-7 77459-78-0 827031-75-4 955376-51-9
61941-79-5

海关

海关编码	2933399090
中文概述	2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%