593-12-4

• 常用中文名：1-溴-8-氟辛烷
• 常用英文名：1-bromo-8-fluorooctane
• CAS号：593-12-4
• 分子式：C₈H₁₆BrF
• 分子量：211.11500
• 发布时间：2016-11-13 05:56:33
• 更新时间：2024-01-10 15:21:18

名称

• 中文名: 1-溴-8-氟辛烷
• 英文名: 1-bromo-8-fluorooctane
• 中文别名: 1-氟-8-溴辛烷
• 英文别名: 1-bromo-8-fluoroctane; 8-Fluorooctyl bromide; OCTANE,1-BROMO-8-FLUORO; 8-bromo-1-fluoro-octane; 1-bromo-8-fluoro-octane; 8-Fluor-octylbromid; 1-Brom-8-fluor-octan

物化性质

• 密度: 1.178g/cm3
• 沸点: 224.2ºC at 760 mmHg
• 分子式: C₈H₁₆BrF
• 分子量: 211.11500
• 闪点: 92.3ºC
• 精确质量: 210.04200
• LogP: 3.69140
• 折射率: 1.437
• 储存条件: 室温

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : RG8600000 CHEMICAL NAME : Octane, 1-bromo-8-fluoro- CAS REGISTRY NUMBER : 593-12-4 BEILSTEIN REFERENCE NO. : 1735436 LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C8-H16-Br-F MOLECULAR WEIGHT : 211.15 WISWESSER LINE NOTATION : F8E HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 20 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JOCEAH Journal of Organic Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1936- Volume(issue)/page/year: 21,748,1956 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 20 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CLDND* Compilation of LD50 Values of New Drugs. (J.R. MacDougal, Dept. of National Health and Welfare, Food and Drug Divisions, 35 John St., Ottawa, Ont., Canada)

合成路线

50816-19-8 144-55-8 ~60% 593-12-4

文献：Research Foundation of State University of New York Patent: US4455441 A1, 1984 ;

50816-19-8 ~96% 593-12-4

文献：Tremblay, Amy E.; Tan, Nigel; Whittle, Ed; Hodgson, Derek J.; Dawson, Brian; Buist, Peter H.; Shanklin, John Organic and Biomolecular Chemistry, 2010 , vol. 8, # 6 p. 1322 - 1328

408-27-5 ~% 593-12-4

文献：Dear,R.E.A.; Pattison,F.L.M. Journal of the American Chemical Society, 1963 , vol. 85, p. 622 - 626

4549-32-0 ~% 593-12-4

文献：Pattison; Howell Journal of Organic Chemistry, 1956 , vol. 21, p. 748,749