101403-24-1

• 常用中文名：(S)-5-甲氧基-1,2,3,4-四氢-N-丙基-2-萘胺
• 常用英文名：(S)-5-METHOXY-N-PROPYL-1,2,3,4-TETRAHYDRONAPHTHALEN-2-AMINE
• CAS号：101403-24-1
• 分子式：C₁₄H₂₁NO
• 分子量：219.323
• 相关类别： 医药中间体 原料药中间体
• 发布时间：2018-10-16 19:39:35
• 更新时间：2024-01-13 10:30:27

名称

• 中文名: (S)-5-甲氧基-1,2,3,4-四氢-N-丙基-2-萘胺
• 英文名: (2S)-5-methoxy-N-propyl-1,2,3,4-tetrahydronaphthalen-2-amine
• 英文别名: (2S)-5-Methoxy-N-propyl-1,2,3,4-tetrahydronaphthalen-2-amine; (S)-5-Methoxy-N-propyl-1,2,3,4-tetrahydronaphthalen-2-amine; (-)-(2S)-2-(n-propylamino)-5-methoxytetralin; (S)-(5-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)propylamine; (-)-5-methoxy-N-propyl-1,2,3,4-tetrahydronaphthalen-2-amine; (S)-1,2,3,4-tetrahydro-5-methoxy-N-propyl-2-Naphthalenamine(Rotigotine); (S)-(-)-2-(N-propylamino)-5-methoxytetraline; (S)-(-)-2-(N-propylamino)-5-methoxytetralin; (2S)-5-Methoxy-N-propyl-1,2,3,4-tetrahydro-2-naphthalenamine; 2-Naphthalenamine, 1,2,3,4-tetrahydro-5-methoxy-N-propyl-, (2S)-; (S)-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propylamine hydrochloride

物化性质

• 密度: 1.0±0.1 g/cm3
• 沸点: 346.1±42.0 °C at 760 mmHg
• 分子式: C₁₄H₂₁NO
• 分子量: 219.323
• 闪点: 143.3±17.3 °C
• 精确质量: 219.162308
• PSA: 21.26000
• LogP: 3.17
• 蒸汽压: 0.0±0.8 mmHg at 25°C
• 折射率: 1.533

安全

• 海关编码: 2922299090

合成路线

3904-24-3 ~96% 101403-24-1

文献：KANDULA, Mahesh Patent: WO2013/168033 A1, 2013 ; Location in patent: Paragraph 0099; 00100 ;

1222074-03-4 ~98% 101403-24-1

文献：Marquillas Olondriz, Francisco; Pomares Marco, Marta Patent: US2011/152543 A1, 2011 ; Location in patent: Page/Page column 3 ;

101403-23-0 ~85% 101403-24-1

文献：Seiler, Max P.; Stoll, Andre P.; Closse, Annemarie; Frick, Willy; Jaton, Annelise; Vigouret, Jean-Marie Journal of Medicinal Chemistry, 1986 , vol. 29, # 6 p. 912 - 917

244239-67-6 ~92% 101403-24-1

文献：Homan, Evert J.; Copinga, Swier; Unelius, Lena; Jackson, David M.; Wikstroem, Hkan V.; Grol, Cor J. Bioorganic and Medicinal Chemistry, 1999 , vol. 7, # 7 p. 1263 - 1271

58349-23-8 ~% 101403-24-1

文献：Journal of Medicinal Chemistry, , vol. 29, # 6 p. 912 - 917

32940-15-1 ~% 101403-24-1

文献：Journal of Medicinal Chemistry, , vol. 34, # 11 p. 3235 - 3241

78598-91-1 ~% 101403-24-1

文献：Journal of Medicinal Chemistry, , vol. 38, # 8 p. 1319 - 1329

136247-07-9 ~% 101403-24-1

文献：Journal of Medicinal Chemistry, , vol. 34, # 11 p. 3235 - 3241

58349-23-8 802294-64-0 ~% 101403-24-1

文献：Journal of Medicinal Chemistry, , vol. 34, # 11 p. 3235 - 3241

海关

海关编码	2922299090
中文概述	2922299090. 其他氨基(萘酚、酚)及醚、酯〔包括它们的盐, 但含有一种以上含氧基的除外〕. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
申报要素	品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装
Summary	2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%