17321-47-0

• 常用中文名：O,O-二甲基硫代磷酰胺
• 常用英文名：O,O-dimethylamidothiophosphate
• CAS号：17321-47-0
• 分子式：C₂H₈NO₂PS
• 分子量：141.12900
• 相关类别： 化学农药原药 杀虫剂中间体
• 发布时间：2018-09-06 19:42:33
• 更新时间：2024-01-02 19:01:42
• 【用途一】
  主要用作甲胺磷、乙酰甲胺磷的中间体
  【用途二】
  O，O-二甲基硫代磷酰胺简称精胺或精酰胺，是合成甲胺磷的中间体。

名称

• 中文名: O,O-二甲基硫代磷酰胺
• 英文名: O,O-Dimethyl phosphoramidothioate
• 中文别名: 精胺
• 英文别名: O,O-Dimethylthiophosphorylamide; O,O-Dimethyl thiophosphoramidate; O,O-DimethylPhosphoramidothionate; Thiophosphorsaeure-O,O-dimethylesteramid; O,O-Dimethyl Phosphoroamido Thioate; EINECS 241-342-2; O,O-Dimethylthiophosphorsaeure-amid; O,O-DIMETHYL THIOPHORAMIDOTHIONATE; dimethoxythiophosphorylamine; O,O-Dimethyl-thiophosphorsaeureesteramid; O,O-dimethylamidothiophosphate; E-118 amide

物化性质

• 密度: 0.925 g/cm3
• 沸点: 150ºC (5 mmHg)
• 熔点: 26-30ºC
• 分子式: C₂H₈NO₂PS
• 分子量: 141.12900
• 闪点: 110ºC
• 精确质量: 141.00100
• PSA: 86.38000
• LogP: 1.81330
• 外观性状: 淡黄色或无色透明液体
• 蒸汽压: 0.000683mmHg at 25°C
• 储存条件: 2~8℃
• 分子结构:

  1、 摩尔折射率：32.47

  2、 摩尔体积（cm³/mol）：109.9

  3、 等张比容（90.2K）：293.6

  4、 表面张力（dyne/cm）：50.8

  5、 极化率（10-24cm3）：12.87

• 计算化学:

  1.疏水参数计算参考值（XlogP）:0.5

  2.氢键供体数量:1

  3.氢键受体数量:4

  4.可旋转化学键数量:2

  5.互变异构体数量:2

  6.拓扑分子极性表面积76.6

  7.重原子数量:7

  8.表面电荷:0

  9.复杂度:87.7

  10.同位素原子数量:0

  11.确定原子立构中心数量:0

  12.不确定原子立构中心数量:0

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:1

• 更多:

  1.性状：无色液体

  2.沸点（ºC，160Pa）：72~73

  3.溶解性：不溶于水

MSDS

Material Safety Data Sheet Section1. Identification of the substance Product Name: O,O-Dimethyl phosphoramidothioate Synonyms: Section2. Hazards identification Harmful by inhalation, in contact with skin, and if swallowed. Section3. Composition/information on ingredients. Ingredient name:O,O-Dimethyl phosphoramidothioate CAS number:17321-47-0 Section4. First aid measures Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing contaminated clothing and shoes. If irritation persists, seek medical attention. Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical attention. Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention. Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention. Section5. Fire fighting measures In the event of a fire involving this material, alone or in combination with other materials, use dry powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus should be worn. Section6. Accidental release measures Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national standards. Respiratory precaution:Wear approved mask/respirator Hand precaution:Wear suitable gloves/gauntlets Skin protection:Wear suitable protective clothing Eye protection:Wear suitable eye protection Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container for disposal. See section 12. Environmental precautions: Do not allow material to enter drains or water courses. Section7. Handling and storage Handling:This product should be handled only by, or under the close supervision of, those properly qualified in the handling and use of potentially hazardous chemicals, who should take into account the fire, health and chemical hazard data given on this sheet. Store in closed vessels, refrigerated. Storage: Section8. Exposure Controls / Personal protection Engineering Controls: Use only in a chemical fume hood. Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles. General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse. Section9. Physical and chemical properties Appearance:Not specified Boiling point:No data No data Melting point: Flash point:No data Density:No data Molecular formula:C2H8NO2PS Molecular weight:141.1 Section10. Stability and reactivity Conditions to avoid: Heat, flames and sparks. Materials to avoid: Oxidizing agents. Possible hazardous combustion products: Carbon monoxide, nitrogen oxides, sulfur oxides. Section11. Toxicological information No data. Section12. Ecological information No data. Section13. Disposal consideration Arrange disposal as special waste, by licensed disposal company, in consultation with local waste disposal authority, in accordance with national and regional regulations. Section14. Transportation information Non-harzardous for air and ground transportation. Section15. Regulatory information No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302, or have known CAS numbers that exceed the threshold reporting levels established by SARA Title III, Section 313. SECTION 16 - ADDITIONAL INFORMATION N/A

安全

• 危害码 (欧洲): C:Corrosive;
• 风险声明 (欧洲): R34
• 安全声明 (欧洲): S26-S37-S61-S60
• 危险品运输编码: UN 3077 9/PG 3
• WGK德国: 2
• RTECS号: WZ6475000
• 包装等级: III
• 海关编码: 2929909090

合成路线

2524-03-0 ~99% 17321-47-0

文献：Ghadimi; Asad-Samani; Ebrahimi-Valmoozi Journal of the Iranian Chemical Society, 2011 , vol. 8, # 3 p. 717 - 726

124-41-4 65960-90-9 ~% 17321-47-0

文献：Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 1646 - 1655

上下游产品

上游产品  3
2524-03-0 124-41-4 65960-90-9
下游产品  4
10265-92-6 2697-42-9 118083-18-4 42072-27-5

制备

其制备方法是以甲基氯化物为原料进行胺化而得。
将一定量的甲基氯化物和适量溶剂投入搪瓷反应釜内，在搅拌下冷却到0℃左右，再将一定量的氨水慢慢滴入，控制反应温度在20℃左右，约1.5h加完，保温0.5h后取样分析，以检测不到甲基氯化物色谱峰为终点。将物料抽入萃取釜静置分层，油层即为粗胺产品，再经升降膜系统脱溶后即得到精酰胺，含量90％～93%，水分含量低于0.2％。

海关

海关编码	2929909090
中文概述	2929909090 其他含氮基化合物. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:30.0%
申报要素	品名, 成分含量, 用途
Summary	2929909090 other compounds with other nitrogen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%