前往化源商城
入驻化源商城

72141-57-2

72141-57-2结构式
72141-57-2结构式
  • 常用中文名:洛硫嗪
  • 常用英文名:Losulazine
  • CAS号:72141-57-2
  • 分子式:C27H22F4N4O3S
  • 分子量:558.54700
  • 发布时间:2018-09-18 16:06:50
  • 更新时间:2024-01-06 07:03:29

化源商城直购

中文名 洛硫嗪
英文名 [4-(4-fluorophenyl)sulfonylpiperazin-1-yl]-[4-[[7-(trifluoromethyl)quinolin-4-yl]amino]phenyl]methanone
英文别名 Losulazina
Losulazine
Losulazinum
密度 1.454g/cm3
沸点 695.7ºC at 760 mmHg
分子式 C27H22F4N4O3S
分子量 558.54700
闪点 374.5ºC
精确质量 558.13500
PSA 90.99000
LogP 6.31260
折射率 1.638

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TM0829800
CHEMICAL NAME :
Piperazine, 1-((4-fluorophenyl)sulfonyl)-4-(4-((7-(trifluoromethy l)-4-quinolinyl)amino) benzoyl)-
CAS REGISTRY NUMBER :
72141-57-2
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C27-H22-F4-N4-O3-S
MOLECULAR WEIGHT :
558.59

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>3160 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 29,133,1986 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
168 mg/kg
SEX/DURATION :
lactating female 21 day(s) post-birth
TOXIC EFFECTS :
Reproductive - Effects on Newborn - weaning or lactation index (e.g., # alive at weaning per # alive at day 4) Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain) Reproductive - Effects on Newborn - physical
REFERENCE :
TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 33,36C,1986

上游产品  2

下游产品  0