23001-29-8

23001-29-8结构式

常用中文名：1',3',3'-三甲基-6-羟基螺环
常用英文名：Spiro[2H-1-benzopyran-2,2'-[2H]indol]-6-ol,1',3'-dihydro-1',3',3'-trimethyl-
CAS号：23001-29-8
分子式：C₁₉H₁₉NO₂
分子量：293.36000
相关类别：医药中间体杂环化合物吡喃类化合物
发布时间：2018-12-27 18:23:51
更新时间：2024-01-18 13:41:14

中文名	1’,3’,3’-三甲基-6-羟基螺环
英文名	1',3',3'-trimethylspiro[chromene-2,2'-indole]-6-ol
中文别名	1',3',3'-三甲基-6-羟基螺环
英文别名	6-hydroxy spiropyran 1′,3′,3′-Trimethyl-6-hydroxyspiro(2H-1-benzopyran-2,2′-indoline)

密度	1.27g/cm3
沸点	469.6ºC at 760mmHg
分子式	C₁₉H₁₉NO₂
分子量	293.36000
闪点	237.8ºC
精确质量	293.14200
PSA	32.70000
LogP	3.98670
外观性状	Powder \| Light brown to purple
蒸汽压	1.92E-09mmHg at 25°C
折射率	1.678
储存条件	室温

Name:	1 3 3 -Trimethyl-6-hydroxyspiro (2h-1-benzopyran-2 2 -indoline) Material Safety Data Sheet
Synonym:
CAS:	23001-29-8

Section 1 - Chemical Product MSDS Name:1 3 3 -Trimethyl-6-hydroxyspiro (2h-1-benzopyran-2 2 -indoline) Material Safety Data Sheet
Synonym:

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS#	Chemical Name	content	EINECS#
23001-29-8	1',3',3'-Trimethyl-6-hydrospiro(2h-1-b	100	unlisted

Hazard Symbols: None Listed.
Risk Phrases: None Listed.

Section 3 - HAZARDS IDENTIFICATION

EMERGENCY OVERVIEW
The toxicological properties of this material have not been fully investigated.
Potential Health Effects
Eye:
Dust may cause mechanical irritation. The toxicological properties of this material have not been fully investigated.
Skin:
May cause skin irritation. The toxicological properties of this material have not been fully investigated.
Ingestion:
May cause digestive tract disturbances. The toxicological properties of this substance have not been fully investigated.
Inhalation:
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
Chronic:
No information found.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or appropriate foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Clean up spills immediately, observing precautions in the Protective Equipment section. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Avoid generating dusty conditions. Provide ventilation.

Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 23001-29-8: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Solid
Color: purple
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 0 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C19H19NO2
Molecular Weight: 293.36

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, dust generation, strong oxidants.
Incompatibilities with Other Materials:
Oxidizing agents.
Hazardous Decomposition Products:
Irritating and toxic fumes and gases.
Hazardous Polymerization: Has not been reported

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 23001-29-8 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
1',3',3'-Trimethyl-6-hydrospiro(2h-1-benzopyran-2,2'-indoline) - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION

Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
S 28A After contact with skin, wash immediately with
plenty of water.
S 37 Wear suitable gloves.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 23001-29-8: No information available.
Canada
CAS# 23001-29-8 is listed on Canada's NDSL List.
CAS# 23001-29-8 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 23001-29-8 is listed on the TSCA inventory.

SECTION 16 - ADDITIONAL INFORMATION
N/A

风险声明 (欧洲)	36/37/38
安全声明 (欧洲)	24/25
海关编码	2934999090

118-12-7

1194-98-5

~97%

23001-29-8

文献：Rohadi, Atisya; Hasbullah, Siti Aishah; Lazim, Azwan Mat; Nordin, Rumaisa Heterocycles, 2014 , vol. 89, # 4 p. 1017 - 1024

上游产品 2
118-12-7 1194-98-5
下游产品 2
1194-98-5 56979-56-7

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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