60232-85-1

• 常用中文名：4-Hydroxy Phencyclidine
• 常用英文名：4-Hydroxy Phencyclidine
• CAS号：60232-85-1
• 分子式：C₁₇H₂₅NO
• 分子量：259.38600
• 发布时间：2018-07-04 17:42:55
• 更新时间：2024-01-12 19:34:47
• 1-(1-Phenylcyclohexyl)-4-hydroxypiperidine is an analytical reference standard that is structurally categorized as an arylcyclohexylamine.

名称

• 英文名: 4-Hydroxy Phencyclidine
• 英文别名: 1-(1-phenylcyclohexyl)piperidin-4-ol

物化性质

• 密度: 1.093g/cm3
• 沸点: 400.9ºC at 760 mmHg
• 分子式: C₁₇H₂₅NO
• 分子量: 259.38600
• 闪点: 106.1ºC
• 精确质量: 259.19400
• PSA: 23.47000
• LogP: 3.24060
• 折射率: 1.574
• 储存条件: -20°C，密闭，干燥

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : TN2274000 CHEMICAL NAME : Piperidine, 1-(1-phenylcyclohexyl)-4-hydroxy- CAS REGISTRY NUMBER : 60232-85-1 LAST UPDATED : 199706 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C17-H25-N-O MOLECULAR WEIGHT : 259.43 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 434 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 34,197,1982

合成路线

108-86-1 60756-86-7 106-93-4 ~% 60232-85-1

文献：Abbott Laboratories Patent: US5124457 A1, 1992 ;

77-10-1 ~% 60232-85-1 60756-83-4 77160-83-9 详细

文献：Masumoto; Takeuchi; Ohta; Hirobe Chemical and Pharmaceutical Bulletin, 1989 , vol. 37, # 7 p. 1788 - 1794

108-94-1 ~% 60232-85-1

文献：Al-Deeb Arzneimittel-Forschung/Drug Research, 1994 , vol. 44, # 10 p. 1141 - 1144

5382-17-2 ~% 60232-85-1

文献：Al-Deeb Arzneimittel-Forschung/Drug Research, 1994 , vol. 44, # 10 p. 1141 - 1144

60756-86-7 ~% 60232-85-1

文献：Itzhak, Yossef; Kalir, Asher; Weissman, Ben Avi; Cohen, Sasson Journal of Medicinal Chemistry, 1981 , vol. 24, # 5 p. 496 - 499

108-86-1 344260-33-9 ~% 60232-85-1

文献：Itzhak, Yossef; Kalir, Asher; Weissman, Ben Avi; Cohen, Sasson Journal of Medicinal Chemistry, 1981 , vol. 24, # 5 p. 496 - 499

956-90-1 ~% 60232-85-1 78165-07-8

文献：Hufford; Baker; Clark Journal of Pharmaceutical Sciences, 1981 , vol. 70, # 2 p. 155 - 158

77-10-1 ~% 60232-85-1 60756-84-5

文献：Addison, J. B. Pharmaceutical Chemistry Journal, 1981 , vol. 15, # 3 p. 215 - 217 Khimiko-Farmatsevticheskii Zhurnal, 1981 , vol. 15, # 3 p. 110 - 113

956-90-1 ~% 60232-85-1 78165-06-7 78165-07-8

文献：Hufford; Baker; Clark Journal of Pharmaceutical Sciences, 1981 , vol. 70, # 2 p. 155 - 158

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108-86-1 60756-86-7 106-93-4 77-10-1
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