119322-88-2

• 常用中文名：(4S,5S)-4,5-二(氨甲基)-2,2-二甲基二氧杂烷
• 常用英文名：(4s,5s)-4,5-di(aminomethyl)-2,2-dimethyldioxolane
• CAS号：119322-88-2
• 分子式：C₇H₁₆N₂O₂
• 分子量：160.21400
• 发布时间：2018-12-25 18:48:18
• 更新时间：2024-01-09 16:36:57

名称

• 中文名: (4S,5S)-4,5-二(氨甲基)-2,2-二甲基二氧杂烷
• 英文名: (4s,5s)-4,5-di(aminomethyl)-2,2-dimethyldioxolane

物化性质

• 沸点: 47-48ºC
• 分子式: C₇H₁₆N₂O₂
• 分子量: 160.21400
• 闪点: 98.8ºC
• 精确质量: 160.12100
• PSA: 70.50000
• LogP: 0.82450
• 蒸汽压: 0.0486mmHg at 25°C
• 储存条件:

  密闭于阴凉干燥环境中

• 稳定性:

  遵照规定使用和储存则不会分解。

• 分子结构:

  1、 摩尔折射率：42.82

  2、 摩尔体积（m³/mol）：158.7

  3、 等张比容（90.2K）：399.1

  4、 表面张力（dyne/cm）：40.0

  5、 极化率（10^-24cm³）：16.97

• 更多:

  1. 性状：无可用

  2. 密度（g/mL,25/4℃）：无可用

  3. 相对蒸汽密度（g/mL,空气=1）：无可用

  4. 熔点（ºC）：无可用

  5. 沸点（ºC,常压）：47-48

  6. 沸点（ºC,5.2kPa）：无可用

  7. 折射率：1.4655

  8. 闪点（ºC）：无可用

  9. 比旋光度（º）：无可用

  10. 自燃点或引燃温度（ºC）：无可用

  11. 蒸气压（kPa,25ºC）：无可用

  12. 饱和蒸气压（kPa,60ºC）：无可用

  13. 燃烧热（KJ/mol）：无可用

  14. 临界温度（ºC）：无可用

  15. 临界压力（KPa）：无可用

  16. 油水（辛醇/水）分配系数的对数值：无可用

  17. 爆炸上限（%,V/V）：无可用

  18. 爆炸下限（%,V/V）：无可用

  19. 溶解性：无可用

MSDS

Name: (4S 5S)-4 5-Di(aminomethyl)-2 2-dimethyldioxolane 99+% Material Safety Data Sheet Synonym: (4S-trans)-2,2-Dimethyl-1,3-dioxolane-4,5-dimethanamine CAS: 119322-88-2 Section 1 - Chemical Product MSDS Name:(4S 5S)-4 5-Di(aminomethyl)-2 2-dimethyldioxolane 99+% Material Safety Data Sheet Synonym:(4S-trans)-2,2-Dimethyl-1,3-dioxolane-4,5-dimethanamine Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 119322-88-2 (4S,5S)-4,5-Di(aminomethyl)-2,2-dimeth >99 unlisted Hazard Symbols: None Listed. Risk Phrases: None Listed. Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Hygroscopic (absorbs moisture from the air).The toxicological properties of this material have not been fully investigated. Potential Health Effects Eye: May cause eye irritation. Skin: May cause skin irritation. Ingestion: May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated. Inhalation: May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. Chronic: No information found. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Ingestion: Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas. Runoff from fire control or dilution water may cause pollution. Extinguishing Media: Use agent most appropriate to extinguish fire. Use water spray, dry chemical, carbon dioxide, or appropriate foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Provide ventilation. Section 7 - HANDLING and STORAGE Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Storage: Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Store protected from moisture. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 119322-88-2: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Liquid Color: clear, colorless Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: 47-48 deg C Freezing/Melting Point: Not available. Autoignition Temperature: Not applicable. Flash Point: Not applicable. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: soluble Specific Gravity/Density: Molecular Formula: C7H16N2O2 Molecular Weight: 160.22 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Stable under normal temperatures and pressures. Conditions to Avoid: Excess heat, exposure to moist air or water. Incompatibilities with Other Materials: Strong oxidizing agents. Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 119322-88-2 unlisted. LD50/LC50: Not available. Carcinogenicity: (4S,5S)-4,5-Di(aminomethyl)-2,2-dimethyldioxolane - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Not regulated as a hazardous material. IMO Not regulated as a hazardous material. RID/ADR Not regulated as a hazardous material. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: Not available. Risk Phrases: Safety Phrases: S 24/25 Avoid contact with skin and eyes. WGK (Water Danger/Protection) CAS# 119322-88-2: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 119322-88-2 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 119322-88-2 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A

毒性和生态

生态学数据: 该物质对环境可能有危害，对水体应给予特别注意。

合成路线

6134-83-4 ~92% 119322-88-2

文献：Star, Alexander; Goldberg, Israel; Lemcoff, N. Gabriel; Fuchs, Benzion European Journal of Organic Chemistry, 1999 , # 9 p. 2033 - 2043

146144-45-8 ~95% 119322-88-2

文献：Sunkyong Industries, Ltd. Patent: US5395947 A1, 1995 ;

119209-15-3 ~26% 119322-88-2

文献：Haines, Alan H.; Morley, Christopher; Murrer, Barry A. Journal of Medicinal Chemistry, 1989 , vol. 32, # 4 p. 742 - 745

59779-75-8 ~% 119322-88-2

文献：Tetrahedron Asymmetry, , vol. 17, # 14 p. 2101 - 2107

37031-29-1 ~% 119322-88-2

文献：Bioorganic and Medicinal Chemistry, , vol. 13, # 3 p. 755 - 764

104769-25-7 77-76-9 ~% 119322-88-2

文献：Kim, Ki Hyun; Choi, Sang Un; Son, Mi Won; Lee, Kang Ro Chemical and Pharmaceutical Bulletin, 2010 , vol. 58, # 11 p. 1532 - 1535

77-76-9 ~% 119322-88-2

文献：Tetrahedron, , vol. 60, # 35 p. 7743 - 7754

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