267876-28-8

• 常用中文名：2,2-二氟-2-(2-吡啶基)乙酸乙酯
• 常用英文名：ETHYL 2,2-DIFLUORO-2-(PYRIDIN-2-YL)ACETATE
• CAS号：267876-28-8
• 分子式：C₉H₉F₂NO₂
• 分子量：201.17000
• 发布时间：2018-12-28 12:53:08
• 更新时间：2024-01-13 09:02:00

名称

• 中文名: 2,2-二氟-2-(2-吡啶)乙酸乙酯
• 英文名: ethyl 2,2-difluoro-2-pyridin-2-ylacetate
• 中文别名: 2,2-二氟-2-(2-吡啶基)乙酸乙酯; 2,2-二氟-(2-吡啶基)-乙酸乙酯
• 英文别名: ethyl pyridin-2-yldifluoroacetate; 2,2-difluoro-2-pyridin-2-ylacetic acid ethyl ester; ethyl 2,2-difluoro-2-pyridyl acetate

物化性质

• 密度: 1.228g/cm3
• 沸点: 244.2ºC at 760mmHg
• 分子式: C₉H₉F₂NO₂
• 分子量: 201.17000
• 闪点: 101.5ºC
• 精确质量: 201.06000
• PSA: 39.19000
• LogP: 1.73650
• 外观性状: 淡黄色液体
• 蒸汽压: 0.031mmHg at 25°C
• 折射率: 1.46
• 储存条件: 2-8℃

安全

• 危害码 (欧洲): F: Flammable;
• 海关编码: 2933399090

合成路线

109-04-6 667-27-6 ~81% 267876-28-8

文献：Ashwood, Michael S.; Alabaster, Ramon J.; Cottrell, Ian F.; Cowden, Cameron J.; Davies, Antony J.; Dolling, Ulf H.; Emerson, Khateeta M.; Gibb, Andrew D.; Hands, David; Wallace, Debra J.; Wilson, Robert D. Organic Process Research and Development, 2004 , vol. 8, # 2 p. 192 - 200

38078-09-0 55104-63-7 ~% 267876-28-8

文献：Merck and Co., Inc. Patent: US6455532 B1, 2002 ; US 6455532 B1

55104-63-7 ~77% 267876-28-8

文献：Ashwood, Michael S.; Alabaster, Ramon J.; Cottrell, Ian F.; Cowden, Cameron J.; Davies, Antony J.; Dolling, Ulf H.; Emerson, Khateeta M.; Gibb, Andrew D.; Hands, David; Wallace, Debra J.; Wilson, Robert D. Organic Process Research and Development, 2004 , vol. 8, # 2 p. 192 - 200

2739-98-2 ~% 267876-28-8

文献：Burgey, Christopher S.; Robinson, Kyle A.; Lyle, Terry A.; Sanderson, Philip E. J.; Lewis, S. Dale; Lucas, Bobby J.; Krueger, Julie A.; Singh, Rominder; Miller-Stein, Cynthia; White, Rebecca B.; Wong, Bradley; Lyle, Elizabeth A.; Williams, Peter D.; Coburn, Craig A.; Dorsey, Bruce D.; Barrow, James C.; Stranieri, Maria T.; Holahan, Marie A.; Sitko, Gary R.; Cook, Jacquelynn J.; McMasters, Daniel R.; McDonough, Colleen M.; Sanders, William M.; Wallace, Audrey A.; Clayton, Franklin C.; Bohn, Dennis; Leonard, Yvonne M.; Detwiler Jr., Theodore J.; Lynch Jr., Joseph J.; Yan, Youwei; Chen, Zhongguo; Kuo, Lawrence; Gardell, Stephen J.; Shafer, Jules A.; Vacca, Joseph P. Journal of Medicinal Chemistry, 2003 , vol. 46, # 4 p. 461 - 473

109-04-6 ~% 267876-28-8

文献：Ashwood, Michael S.; Alabaster, Ramon J.; Cottrell, Ian F.; Cowden, Cameron J.; Davies, Antony J.; Dolling, Ulf H.; Emerson, Khateeta M.; Gibb, Andrew D.; Hands, David; Wallace, Debra J.; Wilson, Robert D. Organic Process Research and Development, 2004 , vol. 8, # 2 p. 192 - 200

海关

海关编码	2933399090
中文概述	2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%