332099-01-1

• 常用中文名：2-氯-6H-噻吩并[2,3-b]吡咯-5-羧酸乙酯
• 常用英文名：2-Chloro-6H-thieno[2,3-b]pyrrole-5-carboxylic acid ethyl ester
• CAS号：332099-01-1
• 分子式：C₉H₈ClNO₂S
• 分子量：229.68300
• 发布时间：2018-12-27 18:58:01
• 更新时间：2024-01-10 05:32:15

名称

• 中文名: 2-氯-6H-噻吩并[2,3-b]吡咯-5-羧酸乙酯
• 英文名: ethyl 2-chloro-6H-thieno[2,3-b]pyrrole-5-carboxylate

物化性质

• 分子式: C₉H₈ClNO₂S
• 分子量: 229.68300
• 精确质量: 228.99600
• PSA: 70.33000
• LogP: 3.05950

合成路线

35357-56-3 ~90% 332099-01-1

文献：Cai, Hui; Carruthers, Nicholas I.; Dvorak, Curt A.; Edwards, James P.; Kwok, Annette K. Patent: US2004/48878 A1, 2004 ; Location in patent: Page/Page column 9 ; US 20040048878 A1

108-20-3 35357-56-3 ~49% 332099-01-1

文献：Pfizer Inc. Patent: US6399601 B1, 2002 ;

480451-47-6 ~% 332099-01-1

文献：DAIICHI PHARMACEUTICAL CO., LTD. Patent: EP1405852 A1, 2004 ; Location in patent: Page 219 ; EP 1405852 A1

498-62-4 ~% 332099-01-1

文献：Venable, Jennifer D.; Cai, Hui; Chai, Wenying; Dvorak, Curt A.; Grice, Cheryl A.; Jablonowski, Jill A.; Shah, Chandra R.; Kwok, Annette K.; Ly, Kiev S.; Pio, Barbara; Wei, Jianmei; Desai, Pragnya J.; Jiang, Wen; Nguyen, Steven; Ling, Ping; Wilson, Sandy J.; Dunford, Paul J.; Thurmond, Robin L.; Lovenberg, Timothy W.; Karlsson, Lars; Carruthers, Nicholas I.; Edwards, James P. Journal of Medicinal Chemistry, 2005 , vol. 48, # 26 p. 8289 - 8298

335030-68-7 ~% 332099-01-1

文献：Venable, Jennifer D.; Cai, Hui; Chai, Wenying; Dvorak, Curt A.; Grice, Cheryl A.; Jablonowski, Jill A.; Shah, Chandra R.; Kwok, Annette K.; Ly, Kiev S.; Pio, Barbara; Wei, Jianmei; Desai, Pragnya J.; Jiang, Wen; Nguyen, Steven; Ling, Ping; Wilson, Sandy J.; Dunford, Paul J.; Thurmond, Robin L.; Lovenberg, Timothy W.; Karlsson, Lars; Carruthers, Nicholas I.; Edwards, James P. Journal of Medicinal Chemistry, 2005 , vol. 48, # 26 p. 8289 - 8298