827030-33-1

• 常用中文名：MPI-0441138
• 常用英文名：2-chloro-N-(4-methoxyphenyl)-N-methylquinazolin-4-amine
• CAS号：827030-33-1
• 分子式：C₁₆H₁₄ClN₃O
• 分子量：299.75500
• 发布时间：2016-11-02 15:53:58
• 更新时间：2024-01-30 20:27:05
• MPI-0441138 is a potent inducer of apoptosis and growth inhibition (EC50 = 2 nM for both processes, based on caspase-3 activation and total cellular ATP, respectively) in T47D and HCT116 cells.

名称

• 中文名: MPI-0441138
• 英文名: 2-chloro-N-(4-methoxyphenyl)-N-methylquinazolin-4-amine

物化性质

• 分子式: C₁₆H₁₄ClN₃O
• 分子量: 299.75500
• 精确质量: 299.08300
• PSA: 38.25000
• LogP: 4.05970
• 储存条件: -20°C，密闭，干燥

合成路线

607-68-1 5961-59-1 ~85% 827030-33-1

文献：Sirisoma, Nilantha; Kasibhatla, Shailaja; Pervin, Azra; Zhang, Hong; Jiang, Songchun; Willardsen, J. Adam; Anderson, Mark B.; Baichwal, Vijay; Mather, Gary G.; Jessing, Kevin; Hussain, Raouf; Hoang, Khanh; Pleiman, Christopher M.; Tseng, Ben; Drewe, John; Sui, Xiong Cai Journal of Medicinal Chemistry, 2008 , vol. 51, # 15 p. 4771 - 4779

上下游产品

上游产品  2
607-68-1 5961-59-1
下游产品  0