914613-36-8

• 常用中文名：坎地沙坦西来替昔乙酯
• 常用英文名：2H-2-Ethyl Candesartan Cilexetil
• CAS号：914613-36-8
• 分子式：C₃₅H₃₈N₆O₆
• 分子量：638.71300
• 发布时间：2018-10-15 23:38:20
• 更新时间：2024-01-06 18:08:25

名称

• 中文名: 坎地沙坦西来替昔乙酯
• 英文名: 1-cyclohexyloxycarbonyloxyethyl 2-ethoxy-3-[[4-[2-(2-ethyltetrazol-5-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylate
• 英文别名: 1-{[(cyclohexyloxy)carbonyl]oxy}ethyl 2-ethoxy-1-{[2'-(2-ethyl-2H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-benzimidazole-7-carboxylate; 2-Ethoxy-1-[[2'-(2-ethyl-2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylic Acid 1-[[(Cyclohexyloxy)carbonyl]oxy]ethyl Ester; UNII-ZRT0P1L622; 2-N-ethyl CNS; 2H-2-Ethyl Candesartan Cilexetil; Candesartan Cilexetil EP Impurity F; ±1-(Cyclohexyloxycarbonyloxy)ethyl2-ethoxy-1-{[2’-(N-ethyl-tetrazol-5-yl) biphenyl-4-yl]methyl}benzimidazole-7-carboxylate; Candesartan Cilexetil Impurity 6

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 842.0±75.0 °C at 760 mmHg
• 分子式: C₃₅H₃₈N₆O₆
• 分子量: 638.71300
• 闪点: 463.1±37.1 °C
• 精确质量: 638.28500
• PSA: 132.48000
• LogP: 8.08
• 蒸汽压: 0.0±3.1 mmHg at 25°C
• 折射率: 1.648

安全

• 危险品运输编码: NONH for all modes of transport

合成路线

145040-37-5 ~% 869631-11-8 914613-36-8

文献：TEVA PHARMACEUTICAL INDUSTRIES LTD.; TEVA PHARMACEUTICALS USA, INC. Patent: WO2006/122254 A2, 2006 ; Location in patent: Page/Page column 12; 13 ;

75-03-6 145040-37-5 ~% 914613-35-7 914613-36-8

文献：Havllcek, Jaroslav; Mandelova, Zuzana; Weisemann, Ruediger; Strelec, Ivo; Placek, Lukas; Radl, Stanislav Collection of Czechoslovak Chemical Communications, 2009 , vol. 74, # 2 p. 347 - 362

145040-37-5 ~% 869631-11-8 914613-35-7 914613-36-8

文献：TEVA PHARMACEUTICAL INDUSTRIES LTD.; TEVA PHARMACEUTICALS USA, INC. Patent: WO2006/122254 A2, 2006 ; Location in patent: Page/Page column 12; 13 ;