99780-98-0

• 常用中文名：3-(Boc-氨基)-2-哌啶酮
• 常用英文名：TERT-BUTYL (2-OXOPIPERIDIN-3-YL)CARBAMATE
• CAS号：99780-98-0
• 分子式：C₁₀H₁₈N₂O₃
• 分子量：214.26200
• 发布时间：2018-10-11 16:52:15
• 更新时间：2024-01-06 19:56:33

名称

• 中文名: 3-(Boc-氨基)-2-哌啶酮
• 英文名: 3-(Boc-amino)-2-piperidone
• 中文别名: (2-氧代哌啶-3-基)氨基甲酸叔丁酯
• 英文别名: tert-butyl N-(2-oxopiperidin-3-yl)carbamate

物化性质

• 分子式: C₁₀H₁₈N₂O₃
• 分子量: 214.26200
• 精确质量: 214.13200
• PSA: 74.41000
• LogP: 1.27000
• 储存条件: 室温，干燥

合成路线

1892-22-4 24424-99-5 ~80% 99780-98-0

文献：Thorsett, Eugene D.; Harris, Elbert E.; Aster, Susan D.; Peterson, Elwood R.; Snyder, James P.; et al. Journal of Medicinal Chemistry, 1986 , vol. 29, # 2 p. 251 - 260

21887-64-9 ~64% 99780-98-0

文献：GILEAD SCIENCES, INC.; GUO, Hongyan; KATO, Darryl; KIRSCHBERG, Thorsten, A.; LIU, Hongtao; LINK, John, O.; MITCHELL, Michael, L.; PARRISH, Jay, P.; SQUIRES, Neil; SUN, Jianyu; TAYLOR, James; BACON, Elizabeth, M.; CANALES, Eda; CHO, Aesop; KIM, Choung, U.; COTTELL, Jeromy, J.; DESAI, Manoj, C.; HALCOMB, Randall, L.; KRYGOWSKI, Evan, S.; LAZERWITH, Scott, E.; LIU, Qi; MACKMAN, Richard; PYUN, Hyung-Jung; SAUGIER, Joseph, H.; TRENKLE, James, D.; TSE, Winston, C.; VIVIAN, Randall, W.; SCHROEDER, Scott, D.; WATKINS, William, J.; XU, Lianhong; YANG, Zheng-Yu; KELLAR, Terry; SHENG, Xiaoning; CLARKE, Michael, O'Neil, Hanrahan; CHOU, Chien-hung; GRAUPE, Michael; JIN, Haolun; MCFADDEN, Ryan; MISH, Michael, R.; METOBO, Samuel, E.; PHILLIPS, Barton, W.; VENKATARAMANI, Chandrasekar Patent: WO2010/132601 A1, 2010 ; Location in patent: Page/Page column 504 ;

24424-99-5 138377-80-7 ~% 99780-98-0

文献：TAKEDA PHARMACEUTICAL COMPANY LIMITED; MATSUMOTO, Shigemitsu; ONO, Koji; TOMINARI, Yusuke; KATOH, Taisuke; MIWA, Kazuhiro; HASUOKA, Atsushi; IMAMURA, Shinichi Patent: WO2013/18929 A1, 2013 ; Location in patent: Paragraph 0789 ; WO 2013/018929 A1

24424-99-5 88763-76-2 ~90% 99780-98-0

文献：Hendricks, Robert Than; Hermann, Johannes; Kondru, Rama; Lou, Yan; Lynch, Stephen M.; Owens, Timothy D.; Soth, Michael Patent: US2011/230414 A1, 2011 ; US 20110230414 A1

1892-22-4 70-26-8 24424-99-5 ~% 99780-98-0

文献：US6184207 B2, ;

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