148901-53-5

• 常用中文名：6-二甲氨基-2-氟-3-甲酰苯甲腈
• 常用英文名：3-cyano-4-dimethylamino-2-fluorobenzaldehyde
• CAS号：148901-53-5
• 分子式：C₁₀H₉FN₂O
• 分子量：192.19000
• 发布时间：2018-12-18 19:22:40
• 更新时间：2024-01-04 19:29:47
• 下载msds

名称

• 中文名: 3-氰基-4-二甲胺基-2-氟代苯甲醛
• 英文名: 6-(dimethylamino)-2-fluoro-3-formylbenzonitrile
• 中文别名: 3-氰基-4-二甲氨基-2-氟苯甲醛; 6-二甲氨基-2-氟-3-甲酰苯甲腈
• 英文别名: 3-Cyano-4-dimethylamino-2-fluorobenzaldehyde; Benzonitrile,6-(dimethylamino)-2-fluoro-3-formyl; 6-(dimethylamino)-2-fluoro-3-formylbenzenecarbonitrile; MFCD00052668

物化性质

• 密度: 1.662g/cm3
• 沸点: 267.6ºC at 760mmHg
• 熔点: 122-124°C
• 分子式: C₁₀H₉FN₂O
• 分子量: 192.19000
• 闪点: 115.6ºC
• 精确质量: 192.07000
• PSA: 44.10000
• LogP: 1.57588
• 蒸汽压: 0.00401mmHg at 25°C
• 折射率: 1.449
• 分子结构:

  1、摩尔折射率：49.53

  2、摩尔体积（cm³/mol）：157.3

  3、等张比容（90.2K）：412.2

  4、表面张力（dyne/cm）：47

  5、介电常数：无可用的

  6、极化率（10^-24cm³）：19.63

  7、单一同位素质量：192.069891 Da

  8、标称质量：192 Da

  9、平均质量：192.1897 Da

• 计算化学:

  1.疏水参数计算参考值（XlogP）:1.3

  2.氢键供体数量:0

  3.氢键受体数量:4

  4.可旋转化学键数量:2

  5.互变异构体数量:无

  6.拓扑分子极性表面积44.1

  7.重原子数量:14

  8.表面电荷:0

  9.复杂度:258

  10.同位素原子数量:0

  11.确定原子立构中心数量:0

  12.不确定原子立构中心数量:0

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:1

• 更多:

  1. 性状：未确定

  2. 密度（g/mL, 20 ℃ ）：未确定

  3. 相对蒸汽密度（g/mL,空气=1）：未确定

  4. 熔点（ºC）：122-124

  5. 沸点（ºC,常压）：未确定

  6. 沸点（ºC 10mmHg）：未确定

  7. 折射率：未确定

  8. 闪点（ºF）：未确定

  9. 比旋光度（º）：未确定

  10. 自燃点或引燃温度（ºC）：未确定

  11. 蒸气压（kPa,25ºC）：未确定

  12. 饱和蒸气压（kPa,60ºC）：未确定

  13. 燃烧热（KJ/mol）：未确定

  14. 临界温度（ºC）：未确定

  15. 临界压力（KPa）：未确定

  16. 油水（辛醇/水）分配系数的对数值：未确定

  17. 爆炸上限（%,V/V）：未确定

  18. 爆炸下限（%,V/V）：未确定

  19. 溶解性：未确定

MSDS

Name: 6-(Dimethylamino)-2-fluoro-3-formylbenzonitrile 95+% Material Safety Data Sheet Synonym: 3-Cyano-4-dimethylamino-2-fluorobenzaldehyd CAS: 148901-53-5 Section 1 - Chemical Product MSDS Name:6-(Dimethylamino)-2-fluoro-3-formylbenzonitrile 95+% Material Safety Data Sheet Synonym:3-Cyano-4-dimethylamino-2-fluorobenzaldehyd Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 148901-53-5 6-(Dimethylamino)-2-fluoro-3-formylben 95+% unlisted Hazard Symbols: XN Risk Phrases: 20/21/22 36/37/38 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Harmful by inhalation, in contact with skin and if swallowed. Irritating to eyes, respiratory system and skin. Potential Health Effects Eye: Causes eye irritation. Skin: Causes skin irritation. Harmful if absorbed through the skin. Ingestion: Harmful if swallowed. May cause irritation of the digestive tract. Inhalation: Harmful if inhaled. Causes respiratory tract irritation. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Get medical aid. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Section 7 - HANDLING and STORAGE Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Storage: Store in a cool, dry place. Store in a tightly closed container. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 148901-53-5: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Solid Color: off-white Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 125 - 127 deg C Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C10H9FN2O Molecular Weight: 192 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Not available. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Reducing agents, oxidizing agents, amines. Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide, hydrogen fluoride gas, fluorine. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 148901-53-5 unlisted. LD50/LC50: Not available. Carcinogenicity: 6-(Dimethylamino)-2-fluoro-3-formylbenzonitrile - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Shipping Name: NITRILES, SOLID, TOXIC, N.O.S.* Hazard Class: 6.1 UN Number: 3276 Packing Group: III IMO Shipping Name: NITRILES, TOXIC, N.O.S. Hazard Class: 6.1 UN Number: 3276 Packing Group: III RID/ADR Shipping Name: NITRILES, TOXIC, N.O.S. Hazard Class: 6.1 UN Number: 3276 Packing group: III Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XN Risk Phrases: R 20/21/22 Harmful by inhalation, in contact with skin and if swallowed. R 36/37/38 Irritating to eyes, respiratory system and skin. Safety Phrases: S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36/37/39 Wear suitable protective clothing, gloves and eye/face protection. WGK (Water Danger/Protection) CAS# 148901-53-5: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 148901-53-5 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 148901-53-5 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A

安全

• 危害码 (欧洲): T
• 风险声明 (欧洲): R20/21/22
• 安全声明 (欧洲): S26-S36/37/39