26447-14-3

• 常用中文名：甲苯基缩水甘油醚
• 常用英文名：Cresyl glycidyl ether
• CAS号：26447-14-3
• 分子式：C₁₀H₁₂O₂
• 分子量：164.20100
• 发布时间：2018-07-21 21:34:10
• 更新时间：2024-01-08 11:03:22

名称

• 中文名: 甲苯基缩水甘油醚
• 英文名: Cresyl glycidyl ether
• 中文别名: 对叔丁基苯基1-(2,3-环氧)丙基醚; [(甲基苯氧基)甲基]环氧乙烷
• 英文别名: ARALDITE(R) CY 212; tolylglycidylether; ARALDITE 506; ARALDITE 507; cresolglycidylether; EINECS 247-711-4; ARALDITE 502; cresylglycideether; ARALDITE 6005

物化性质

• 密度: 1.14
• 沸点: 258ºC at 760 mmHg
• 分子式: C₁₀H₁₂O₂
• 分子量: 164.20100
• 闪点: 104.3ºC
• 精确质量: 164.08400
• PSA: 21.76000
• LogP: 1.77260
• 外观性状: 无色液体
• 蒸汽压: 0.0227mmHg at 25°C
• 折射率: 1.533
• 稳定性: Stable. Incompatible with strong acids, bases and oxidizing agents. May attack some types of plastic. Combustible.
• 水溶解性: <=0.1 g/100 mL at 21 ºC
• 计算化学:

  1.疏水参数计算参考值（XlogP）:2

  2.氢键供体数量:0

  3.氢键受体数量:2

  4.可旋转化学键数量:3

  5.互变异构体数量:无

  6.拓扑分子极性表面积:21.8

  7.重原子数量:12

  8.表面电荷:0

  9.复杂度:139

  10.同位素原子数量:0

  11.确定原子立构中心数量:0

  12.不确定原子立构中心数量:1

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:1

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : TZ3699000 CHEMICAL NAME : Propane, 1,2-epoxy-3-(tolyloxy)- CAS REGISTRY NUMBER : 26447-14-3 LAST UPDATED : 199710 DATA ITEMS CITED : 13 MOLECULAR FORMULA : C10-H12-O2 MOLECULAR WEIGHT : 164.22 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 5140 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - excitement Behavioral - muscle weakness TYPE OF TEST : LC50 - Lethal concentration, 50 percent kill ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 282 mg/m3 TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - excitement Behavioral - muscle weakness TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1700 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - excitement Behavioral - muscle weakness TYPE OF TEST : LC50 - Lethal concentration, 50 percent kill ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 310 mg/m3 TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - excitement Behavioral - muscle weakness TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 2 mL/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Skin and Appendages - dermatitis, other (after systemic exposure) Nutritional and Gross Metabolic - weight loss or decreased weight gain TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : 1650 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value MUTATION DATA TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Yeast - Saccharomyces cerevisiae DOSE/DURATION : 1 mg/plate REFERENCE : TSCAT* Office of Toxic Substances Report. (U.S. Environmental Protection Agency, Office of Toxic Substances, 401 M St., SW, Washington, DC 20460) Volume(issue)/page/year: OTS 206476 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - T0038 No. of Facilities: 63 (estimated) No. of Industries: 3 No. of Occupations: 6 No. of Employees: 524 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - T0038 No. of Facilities: 119 (estimated) No. of Industries: 10 No. of Occupations: 11 No. of Employees: 4507 (estimated) No. of Female Employees: 1696 (estimated)

安全

• 危害码 (欧洲): Xn: Harmful;
• 风险声明 (欧洲): R61;R25;R36;R37;R38
• 安全声明 (欧洲): 53-26-36/37-45-61
• 危险品运输编码: UN 3082 9
• WGK德国: 3