24255-27-4

• 常用中文名：4-(3-硝基-2-吡啶基)吗啉
• 常用英文名：4-(3-Nitro-2-pyridinyl)morpholine
• CAS号：24255-27-4
• 分子式：C₉H₁₁N₃O₃
• 分子量：209.202
• 发布时间：2018-12-25 15:08:45
• 更新时间：2024-01-13 19:20:45

名称

• 中文名: 4-(3-硝基-2-吡啶基)吗啉
• 英文名: 4-(3-nitropyridin-2-yl)morpholine
• 中文别名: N-(3-硝基-2-吡啶基)吗啉
• 英文别名: N-(3-Nitro-2-pyridyl)morpholine; nitropyridinylmorpholine; 4-(3-nitro-2-pyridyl)morpholine; 4-(3-nitropyridine-2-yl)morpholine; 4-(3-Nitro-2-pyridinyl)morpholine; 4-(3-nitropyridin-2-yl)morpholine; 4-{3-nitro-2-pyridinyl}morpholine; Morpholine, 4-(3-nitro-2-pyridinyl)-; 4-(3-Nitro-pyridin-2-yl)-morpholine

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 375.8±42.0 °C at 760 mmHg
• 熔点: 91-94ºC
• 分子式: C₉H₁₁N₃O₃
• 分子量: 209.202
• 闪点: 181.1±27.9 °C
• 精确质量: 209.080048
• PSA: 71.18000
• LogP: 1.48
• 蒸汽压: 0.0±0.9 mmHg at 25°C
• 折射率: 1.582
• 储存条件: 室温
• 分子结构:

  1、 摩尔折射率：52.69

  2、 摩尔体积（cm³/mol）：157.8

  3、 等张比容（90.2K）：433.6

  4、 表面张力（dyne/cm）：57.0

  5、 极化率（10-24cm3）：20.89

• 计算化学:

  1.疏水参数计算参考值（XlogP）:0.8

  2.氢键供体数量:0

  3.氢键受体数量:5

  4.可旋转化学键数量:1

  5.互变异构体数量:无

  6.拓扑分子极性表面积71.2

  7.重原子数量:15

  8.表面电荷:0

  9.复杂度:225

  10.同位素原子数量:0

  11.确定原子立构中心数量:0

  12.不确定原子立构中心数量:0

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:1

• 更多:

  1. 熔点（ºC）：91~94

MSDS

Name: 4-(3-Nitro-2-pyridinyl)morpholine Material Safety Data Sheet Synonym: CAS: 24255-27-4 Section 1 - Chemical Product MSDS Name:4-(3-Nitro-2-pyridinyl)morpholine Material Safety Data Sheet Synonym: Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 24255-27-4 4-(3-Nitro-2-pyridinyl)morpholine 97+% unlisted Hazard Symbols: XN Risk Phrases: 20/21/22 36/37/38 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Harmful by inhalation, in contact with skin and if swallowed. Irritating to eyes, respiratory system and skin. Potential Health Effects Eye: Causes eye irritation. Skin: Causes skin irritation. Harmful if absorbed through the skin. Ingestion: Harmful if swallowed. May cause irritation of the digestive tract. Inhalation: Harmful if inhaled. May cause respiratory tract irritation. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Get medical aid. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Section 7 - HANDLING and STORAGE Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Storage: Store in a cool, dry place. Store in a tightly closed container. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 24255-27-4: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Solid Color: Orange Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 89 - 90 deg C Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C9H11N3O3 Molecular Weight: 209.21 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Stable. Conditions to Avoid: Incompatible materials, strong oxidants. Incompatibilities with Other Materials: Strong oxidizing agents. Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide. Hazardous Polymerization: Not available. Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 24255-27-4 unlisted. LD50/LC50: Not available. Carcinogenicity: 4-(3-Nitro-2-pyridinyl)morpholine - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Shipping Name: TOXIC SOLID, ORGANIC, N.O.S.* Hazard Class: 6.1 UN Number: 2811 Packing Group: III IMO Shipping Name: TOXIC SOLID, ORGANIC, N.O.S. Hazard Class: 6.1 UN Number: 2811 Packing Group: III RID/ADR Shipping Name: TOXIC SOLID, ORGANIC, N.O.S. Hazard Class: 6.1 UN Number: 2811 Packing group: III Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XN Risk Phrases: R 20/21/22 Harmful by inhalation, in contact with skin and if swallowed. R 36/37/38 Irritating to eyes, respiratory system and skin. Safety Phrases: S 22 Do not breathe dust. S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36/37/39 Wear suitable protective clothing, gloves and eye/face protection. WGK (Water Danger/Protection) CAS# 24255-27-4: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 24255-27-4 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 24255-27-4 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A

安全

• 海关编码: 2934999090

合成路线

110-91-8 5470-18-8 ~95% 24255-27-4

文献：Matulenko, Mark A.; Paight, Ernest S.; Frey, Robin R.; Gomtsyan, Arthur; DiDomenico Jr., Stanley; Jiang, Meiqun; Lee, Chih-Hung; Stewart, Andrew O.; Yu, Haixia; Kohlhaas, Kathy L.; Alexander, Karen M.; McGaraughty, Steve; Mikusa, Joseph; Marsh, Kennan C.; Muchmore, Steven W.; Jakob, Clarissa L.; Kowaluk, Elizabeth A.; Jarvis, Michael F.; Bhagwat, Shripad S. Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 4 p. 1586 - 1605

904326-93-8 ~% 24255-25-2 26820-62-2 134787-63-6 详细

文献：Journal of Organic Chemistry, , vol. 77, # 9 p. 4402 - 4413

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海关

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%