22179-77-7

22179-77-7结构式

常用中文名：3-氯-N-羟基苯甲脒
常用英文名：3-Chlorobenzamidoxime
CAS号：22179-77-7
分子式：C₇H₇ClN₂O
分子量：170.59600
发布时间：2018-09-16 12:08:29
更新时间：2024-01-05 18:02:43

中文名	3-氯-N-羟基苯甲脒
英文名	3-chloro-n'-hydroxybenzenecarboximidamide
中文别名	3-氯-N-羟基苯羰酰肟胺 3-氯苯甲酰胺肟
英文别名	m-chlorobenzamidoxime N-hydroxy-3-chloro-benzamidine m-Chlor-benzamidoxim 3-chlorobenzamidoxime 3-chloro-N-hydroxy-benzamidine 3-Chlorobenzamide oxime 3-Chloro-N-hydroxybenzimidamide

密度	1.36g/cm3
沸点	350.4ºC at 760mmHg
熔点	115ºC
分子式	C₇H₇ClN₂O
分子量	170.59600
闪点	165.7ºC
精确质量	170.02500
PSA	56.11000
LogP	2.13480
外观性状	白色至黄色固体
蒸汽压	1.64E-05mmHg at 25°C
折射率	1.6
储存条件	2-8°C

Name:	3-Chloro-N -hydroxybenzenecarboximidamide Material Safety Data Sheet
Synonym:
CAS:	22179-77-7

Section 1 - Chemical Product MSDS Name:3-Chloro-N -hydroxybenzenecarboximidamide Material Safety Data Sheet
Synonym:

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS#	Chemical Name	content	EINECS#
22179-77-7	2,6-Difluorophenylboronic Acid	97+%	unlisted

Hazard Symbols: XN
Risk Phrases: 20/21/22 36/37/38 44

Section 3 - HAZARDS IDENTIFICATION

EMERGENCY OVERVIEW
Harmful by inhalation, in contact with skin and if swallowed.
Irritating to eyes, respiratory system and skin. Risk of explosion if heated under confinement.
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Causes skin irritation. Harmful if absorbed through the skin.
Ingestion:
Harmful if swallowed. May cause irritation of the digestive tract.
Inhalation:
Harmful if inhaled. Causes respiratory tract irritation.
Chronic:
Not available.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Get medical aid. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Violently decomposes when heated under confinement.
Risk of explosion if heated under confinement.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container.

Section 7 - HANDLING and STORAGE
Handling:
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage:
Store in a cool, dry place. Store in a tightly closed container.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 22179-77-7: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Solid
Color: White
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 114.5 - 117 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C7H7ClN2O
Molecular Weight: 170.6

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Oxidizing agents.
Hazardous Decomposition Products:
Hydrogen chloride, carbon monoxide, oxides of nitrogen, carbon dioxide.
Hazardous Polymerization: Has not been reported

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 22179-77-7 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
2,6-Difluorophenylboronic Acid - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION

Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
Shipping Name: TOXIC SOLID, ORGANIC, N.O.S.*
Hazard Class: 6.1
UN Number: 2811
Packing Group: III
IMO
Shipping Name: TOXIC SOLID, ORGANIC, N.O.S.
Hazard Class: 6.1
UN Number: 2811
Packing Group: III
RID/ADR
Shipping Name: TOXIC SOLID, ORGANIC, N.O.S.
Hazard Class: 6.1
UN Number: 2811
Packing group: III

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XN
Risk Phrases:
R 20/21/22 Harmful by inhalation, in contact with
skin and if swallowed.
R 36/37/38 Irritating to eyes, respiratory system
and skin.
R 44 Risk of explosion if heated under confinement.
Safety Phrases:
S 22 Do not breathe dust.
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
WGK (Water Danger/Protection)
CAS# 22179-77-7: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 22179-77-7 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 22179-77-7 is not listed on the TSCA inventory.
It is for research and development use only.

SECTION 16 - ADDITIONAL INFORMATION
N/A

危害码 (欧洲)	Xn: Harmful;
风险声明 (欧洲)	R20/21/22;R36/37/38;R44
安全声明 (欧洲)	22-26-36/37/39
海关编码	2925290090

766-84-7

~83%

22179-77-7

文献：AstraZeneca AB; NPS PHARMACEUTICALS, INC. Patent: US2007/37820 A1, 2007 ; Location in patent: Page/Page column 21 ; US 20070037820 A1

587-04-2

~93%

22179-77-7

文献：ASTRA ZENECA AB; NPS PHARMACEUTICALS, INC. Patent: WO2004/14881 A2, 2004 ; Location in patent: Page 161 ; WO 2004/014881 A2

上游产品 2
766-84-7 587-04-2
下游产品 2
29203-59-6 51802-78-9

海关编码	2925290090
中文概述	2925290090 其他亚胺及其衍生物，以及它们的盐。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:30.0%
申报要素	品名, 成分含量, 用途
Summary	2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

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