724788-66-3

• 常用中文名：4-溴-6-甲氧基-1,5-萘啶-3-胺
• 常用英文名：4-Bromo-6-methoxy-[1,5]naphthyridin-3-ylamine
• CAS号：724788-66-3
• 分子式：C₉H₈BrN₃O
• 分子量：254.08300
• 发布时间：2018-12-23 20:13:10
• 更新时间：2024-01-16 22:11:19

名称

• 中文名: 4-溴-6-甲氧基-1,5-萘啶-3-胺
• 英文名: 4-Bromo-6-methoxy-1,5-naphthyridin-3-amine
• 英文别名: 4-bromo-6-(methyloxy)-1,5-naphthyridin-3-amine; 4-bromo-6-methoxy-[1,5]naphthyridin-3-ylamine

物化性质

• 分子式: C₉H₈BrN₃O
• 分子量: 254.08300
• 精确质量: 252.98500
• PSA: 61.03000
• LogP: 2.56430

合成路线

724788-65-2 75-65-0 ~% 724788-66-3 724788-67-4

文献：GLAXO GROUP LIMITED Patent: WO2006/17468 A2, 2006 ; Location in patent: Page/Page column 22 ;

724788-67-4 ~73% 724788-66-3

文献：GLAXO GROUP LIMITED Patent: WO2006/17468 A2, 2006 ; Location in patent: Page/Page column 22 ;

6628-77-9 ~% 724788-66-3

文献：Miles, Timothy J.; Axten, Jeffrey M.; Barfoot, Christopher; Brooks, Gerald; Brown, Pamela; Chen, Dongzhao; Dabbs, Steven; Davies, David T.; Downie, David L.; Eyrisch, Susanne; Gallagher, Timothy; Giordano, Ilaria; Gwynn, Michael N.; Hennessy, Alan; Hoover, Jennifer; Huang, Jianzhong; Jones, Graham; Markwell, Roger; Miller, William H.; Minthorn, Elizabeth A.; Rittenhouse, Stephen; Seefeld, Mark; Pearson, Neil Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 24 p. 7489 - 7495

724788-64-1 ~% 724788-66-3

文献：Miles, Timothy J.; Axten, Jeffrey M.; Barfoot, Christopher; Brooks, Gerald; Brown, Pamela; Chen, Dongzhao; Dabbs, Steven; Davies, David T.; Downie, David L.; Eyrisch, Susanne; Gallagher, Timothy; Giordano, Ilaria; Gwynn, Michael N.; Hennessy, Alan; Hoover, Jennifer; Huang, Jianzhong; Jones, Graham; Markwell, Roger; Miller, William H.; Minthorn, Elizabeth A.; Rittenhouse, Stephen; Seefeld, Mark; Pearson, Neil Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 24 p. 7489 - 7495

724788-65-2 ~% 724788-66-3

文献：Miles, Timothy J.; Axten, Jeffrey M.; Barfoot, Christopher; Brooks, Gerald; Brown, Pamela; Chen, Dongzhao; Dabbs, Steven; Davies, David T.; Downie, David L.; Eyrisch, Susanne; Gallagher, Timothy; Giordano, Ilaria; Gwynn, Michael N.; Hennessy, Alan; Hoover, Jennifer; Huang, Jianzhong; Jones, Graham; Markwell, Roger; Miller, William H.; Minthorn, Elizabeth A.; Rittenhouse, Stephen; Seefeld, Mark; Pearson, Neil Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 24 p. 7489 - 7495

53241-90-0 ~% 724788-66-3

文献：Singh, Sheo B.; Kaelin, David E.; Wu, Jin; Miesel, Lynn; Tan, Christopher M.; Meinke, Peter T.; Olsen, David; Lagrutta, Armando; Bradley, Prudence; Lu, Jun; Patel, Sangita; Rickert, Keith W.; Smith, Robert F.; Soisson, Stephen; Wei, Changqing; Fukuda, Hideyuki; Kishii, Ryuta; Takei, Masaya; Fukuda, Yasumichi ACS Medicinal Chemistry Letters, 2014 , vol. 5, # 5 p. 609 - 614

53241-92-2 ~% 724788-66-3

文献：Singh, Sheo B.; Kaelin, David E.; Wu, Jin; Miesel, Lynn; Tan, Christopher M.; Meinke, Peter T.; Olsen, David; Lagrutta, Armando; Bradley, Prudence; Lu, Jun; Patel, Sangita; Rickert, Keith W.; Smith, Robert F.; Soisson, Stephen; Wei, Changqing; Fukuda, Hideyuki; Kishii, Ryuta; Takei, Masaya; Fukuda, Yasumichi ACS Medicinal Chemistry Letters, 2014 , vol. 5, # 5 p. 609 - 614

724788-63-0 ~% 724788-66-3

文献：Miles, Timothy J.; Axten, Jeffrey M.; Barfoot, Christopher; Brooks, Gerald; Brown, Pamela; Chen, Dongzhao; Dabbs, Steven; Davies, David T.; Downie, David L.; Eyrisch, Susanne; Gallagher, Timothy; Giordano, Ilaria; Gwynn, Michael N.; Hennessy, Alan; Hoover, Jennifer; Huang, Jianzhong; Jones, Graham; Markwell, Roger; Miller, William H.; Minthorn, Elizabeth A.; Rittenhouse, Stephen; Seefeld, Mark; Pearson, Neil Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 24 p. 7489 - 7495

上下游产品

上游产品  7
724788-65-2 75-65-0 724788-67-4 6628-77-9
724788-64-1 53241-90-0 724788-63-0
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