36016-97-4

• 常用中文名：2-Acetamido-1,3-thiazol-5-yl thiocyanate
• 常用英文名：2-Acetamido-1,3-thiazol-5-yl thiocyanate
• CAS号：36016-97-4
• 分子式：C₆H₅N₃OS₂
• 分子量：199.25300
• 发布时间：2017-12-06 13:06:54
• 更新时间：2024-01-10 12:58:13

名称

• 英文名: 2-Acetamido-1,3-thiazol-5-yl thiocyanate
• 英文别名: 2-acetylamino-5-thiocyanatothiazole; 2-acetamino-5-thiocyanatothiazole; 2-Acetylamino-5-thiocyanyl-thiazol; 2-Benzolsulfonylamino-4-methyl-5-t-butyl-thiazol

物化性质

• 密度: 1.47g/cm3
• 分子式: C₆H₅N₃OS₂
• 分子量: 199.25300
• 精确质量: 198.98700
• PSA: 122.81000
• LogP: 2.32418
• 折射率: 1.636

合成路线

23056-10-2 ~74% 36016-97-4

文献：Bristol-Myers Squibb Company Patent: US6262096 B1, 2001 ; US 6262096 B1

23056-10-2 108-24-7 ~78% 36016-97-4

文献：Kim, Kyoung Soon; Kimball, S. David; Misra, Raj N.; Rawlins, David B.; Hunt, John T.; Xiao, Hai-Yun; Lu, Songfeng; Qian, Ligang; Han, Wen-Ching; Shan, Weifang; Mitt, Toomas; Cai, Zhen-Wei; Poss, Michael A.; Zhu, Hong; Sack, John S.; Tokarski, John S.; Chang, Chieh Ying; Pavletich, Nikola; Kamath, Amrita; Humphreys, William G.; Marathe, Punit; Bursuker, Isia; Kellar, Kristen A.; Roongta, Urvashi; Batorsky, Roberta; Mulheron, Janet G.; Bol, David; Fairchild, Craig R.; Lee, Francis Y.; Webster, Kevin R. Journal of Medicinal Chemistry, 2002 , vol. 45, # 18 p. 3905 - 3927

540-72-7 ~% 36016-97-4

文献：Hurd; Wehrmeister Journal of the American Chemical Society, 1949 , vol. 71, p. 4007,4009

2719-23-5 1147550-11-5 ~% 36016-97-4

文献：Takatori; Nishida Yakugaku Zasshi, 1951 , vol. 71, p. 1367,1369 Chem.Abstr., 1952 , p. 8099