59878-28-3

• 常用中文名：4-Boc-1-哌嗪甲酰氯
• 常用英文名：4-CHLOROCARBONYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
• CAS号：59878-28-3
• 分子式：C₁₀H₁₇ClN₂O₃
• 分子量：248.70700
• 发布时间：2018-12-28 18:50:57
• 更新时间：2024-01-14 17:44:29

名称

• 中文名: 4-氯羰基-哌嗪-1-羧酸叔丁酯
• 英文名: tert-butyl 4-carbonochloridoylpiperazine-1-carboxylate
• 中文别名: 4-BOC-1-哌嗪甲酰氯
• 英文别名: 1-Piperazinecarboxylicacid,4-(chlorocarbonyl)-,1,1-dimethylethyl ester; 4-chlorocarbonyl-1-t-butoxycarbonylpiperazine; tert-butyl 4-chlorocarbonyl-1-piperazinecarboxylate; 4-(tert-butyloxycarbonyl)piperazine-1-carbonyl chloride; tert-butyl (1-piperazinecarboxylate)-4-carbonyl chloride; 1-(Chlorocarbonyl)-4-(tert-butoxycarbonyl)piperazine; 4-chlorocarbonyl-piperazine-1-carboxylic acid tert-butyl ester; 4-(2-methyl-2-propyloxycarbonyl)piperazine-1-carbonylchloride; tert-Butyl4-chlorocarbonylpiperazine-1-carboxylate; 4-Boc-1-piperazinecarbonylChloride

物化性质

• 分子式: C₁₀H₁₇ClN₂O₃
• 分子量: 248.70700
• 精确质量: 248.09300
• PSA: 49.85000
• LogP: 1.77370
• 储存条件: 室温，干燥

合成路线

32315-10-9 57260-71-6 ~89% 59878-28-3

文献：Brinkman, John A.; Cheung, Adrian Wai-Hing; Firooznia, Fariborz; Guertin, Kevin Richard; Marcopulos, Nicholas; Qi, Lida; Racha, Jagdish Kumar; Sarabu, Ramakanth; Tan, Jenny; Tilley, Jefferson Wright Patent: US2007/270433 A1, 2007 ; Location in patent: Page/Page column 19 ; US 20070270433 A1

75-44-5 57260-71-6 ~% 59878-28-3

文献：Sutton, James C.; Bolton, Scott A.; Hartl, Karen S.; Huang, Ming-Hsing; Jacobs, Glenn; Meng, Wei; Ogletree, Martin L.; Pi, Zulan; Schumacher, William A.; Seiler, Steven M.; Slusarchyk, William A.; Treuner, Uwe; Zahler, Robert; Zhao, Guohua; Bisacchi, Gregory S. Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 21 p. 3229 - 3233

57260-71-6 503-38-8 ~% 59878-28-3

文献：Bristol-Myers Squibb Co. Patent: US6335324 B1, 2002 ; Location in patent: Page column 60 ; US 6335324 B1