194350-95-3

• 常用中文名：1-乙基-4-(叔丁基氧基羰基)哌嗪-2-酮
• 常用英文名：1-ETHYL-4-(TERT-BUTYLOXYCARBONYL)PIPERAZIN-2-ONE
• CAS号：194350-95-3
• 分子式：C₁₁H₂₀N₂O₃
• 分子量：228.28800
• 发布时间：2019-01-02 14:01:13
• 更新时间：2024-01-08 22:51:38

名称

• 中文名: 1-乙基-4-(叔丁基氧基羰基)哌嗪-2-酮
• 英文名: tert-butyl 4-ethyl-3-oxopiperazine-1-carboxylate
• 英文别名: 1-ETHYL-4-(TERT-BUTYLOXYCARBONYL)PIPERAZIN-2-ONE; 4-ethyl-3-oxopiperazine-1-carboxylic acid tert-butyl ester; 1-tert-butoxycarbonyl-4-ethyl-3-oxopiperazine

物化性质

• 密度: 1.087 g/cm3
• 沸点: 348ºC at 760 mmHg
• 分子式: C₁₁H₂₀N₂O₃
• 分子量: 228.28800
• 闪点: 164.3ºC
• 精确质量: 228.14700
• PSA: 49.85000
• LogP: 0.96140

合成路线

76003-29-7 75-03-6 ~81% 194350-95-3

文献：DAIICHI PHARMACEUTICAL CO., LTD. Patent: EP1785418 A1, 2007 ; Location in patent: Page/Page column 72 ;

74-96-4 76003-29-7 ~59% 194350-95-3

文献：Martini, Elisabetta; Ghelardini, Carla; Dei, Silvia; Guandalini, Luca; Manetti, Dina; Melchiorre, Michele; Norcini, Monica; Scapecchi, Serena; Teodori, Elisabetta; Romanelli, Maria Novella Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 3 p. 1431 - 1443

76003-29-7 ~% 194350-95-3

文献：Cumming; Le; Babu; Carroll; Chen; Favreau; Gaspari; Guo; Hobbs; Huang; Iserloh; Kennedy; Kuvelkar; Li; Lowrie; McHugh; Ozgur; Pan; Parker; Saionz; Stamford; Strickland; Tadesse; Voigt; Wang; Wu; Zhang Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 11 p. 3236 - 3241