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66547-10-2

66547-10-2结构式

常用中文名：ANSAMITOCIN P-4
常用英文名：ANSAMITOCIN P-4
CAS号：66547-10-2
分子式：C₃₃H₄₅ClN₂O₉
分子量：649.17100
发布时间：2017-05-11 05:20:08
更新时间：2024-01-17 18:32:47

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英文名	Maytansine, 3-de(2-(acetylmethylamino)-1-oxopropoxy)-3-(3-methyl-1-oxobutoxy)
英文别名	Tam 340 ansamitocin P-4 Maytansinol isovalerate

密度	1.28g/cm3
沸点	838.7ºC at 760 mmHg
分子式	C₃₃H₄₅ClN₂O₉
分子量	649.17100
闪点	461ºC
精确质量	648.28100
PSA	136.16000
LogP	5.10750
折射率	1.58
储存条件	库房通风低温干燥,与食品原料分开存放

CHEMICAL IDENTIFICATION

RTECS NUMBER :: OQ2295000

CHEMICAL NAME :: Maytansine, 3-de(2-(acetylmethylamino)propionyloxy)-3-hydroxy-, isovalerate (ester)

CAS REGISTRY NUMBER :: 66547-10-2

LAST UPDATED :: 199612

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C33-H45-Cl-N2-O9

MOLECULAR WEIGHT :: 649.25

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 625 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Cytogenetic analysis

TEST SYSTEM :: Rodent - mouse Ascites tumor

DOSE/DURATION :: 4 ug/kg

REFERENCE :: CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 40,1707,1980