153248-46-5

• 常用中文名：1-羟基甲基-1-(叔丁氧基羰基氨基甲基)环丙烷
• 常用英文名：[1-[(Boc-amino)methyl]cyclopropyl]methanol
• CAS号：153248-46-5
• 分子式：C₁₀H₁₉NO₃
• 分子量：201.263
• 发布时间：2018-12-01 09:57:23
• 更新时间：2024-01-19 00:16:22

名称

• 中文名: 1-羟基甲基-1-(叔丁氧基羰基氨基甲基)环丙烷
• 英文名: tert-butyl N-[[1-(hydroxymethyl)cyclopropyl]methyl]carbamate
• 中文别名: [1-[(Boc-氨基)甲基]环丙基]甲醇
• 英文别名: (1-Hydroxymethyl-cyclopropylmethyl); -carbamic acid tert-butyl ester; (N-Boc-1-aminomethyl-cycIopropyl)-methanol; Carbamic acid, N-[[1-(hydroxymethyl)cyclopropyl]methyl]-, 1,1-dimethylethyl ester; tert-butyl (1-(hydroxymethyl)cyclo-1-propyl)methylcarbamate; 1,1-dimethylethyl {[1-(hydroxymethyl)cyclopropyl]methyl}carbamate; tert-Butyl ((1-(hydroxymethyl)cyclopropyl)methyl)carbamate; N-tert-butoxycarbonyl-1-aminomethyl-1-cyclopropylmethanol; (1-Hydroxymethyl-cyclopropylmethyl)-carbamic acid tert-butyl ester; tert-Butyl {[1-(hydroxymethyl)cyclopropyl]methyl}carbamate; 2-Methyl-2-propanyl {[1-(hydroxymethyl)cyclopropyl]methyl}carbamate; 1-Hydroxymethyl-1-(Boc-aminomethyl)cyclopropane; TERT-BUTYL N-([1-(HYDROXYMETHYL)CYCLOPROPYL]METHYL)CARBAMATE; N-Boc-1-aminomethyl-cyclopropyl-methanol; [1-[(Boc-amino)methyl]cyclopropyl]methanol

物化性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 311.3±15.0 °C at 760 mmHg
• 分子式: C₁₀H₁₉NO₃
• 分子量: 201.263
• 闪点: 142.0±20.4 °C
• 精确质量: 201.136490
• PSA: 62.05000
• LogP: 0.85
• 蒸汽压: 0.0±1.5 mmHg at 25°C
• 折射率: 1.483
• 储存条件: 室温，干燥

安全

• 海关编码: 2924299090

合成路线

24424-99-5 45434-02-4 ~% 153248-46-5

文献：Buchholz, Mirko; Heiser, Ulrich; Schilling, Stephan; Niestroj, Andre J.; Zunkel, Katrin; Demuth, Hans-Ulrich Journal of Medicinal Chemistry, 2006 , vol. 49, # 2 p. 664 - 677

204376-48-7 ~% 153248-46-5

文献：LEO Pharma A/S; NIELSEN, Simon Feldbaek; VIFIAN, Thomas; HORNEMAN, Anne Marie; LAU, Jesper Faergemann Patent: WO2010/69322 A1, 2010 ; Location in patent: Page/Page column 58 ;

6914-80-3 ~% 153248-46-5

文献：Buchholz, Mirko; Heiser, Ulrich; Schilling, Stephan; Niestroj, Andre J.; Zunkel, Katrin; Demuth, Hans-Ulrich Journal of Medicinal Chemistry, 2006 , vol. 49, # 2 p. 664 - 677

3697-69-6 ~% 153248-46-5

文献：BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BOYER, Stephen, James; GAO, Donghong, Amy; GUO, Xin; KIRRANE, Thomas, Martin, Jr.; SARKO, Christopher, Ronald; SNOW, Roger, John; SOLEYMANZADEH, Fariba; ZHANG, Yunlong Patent: WO2011/71716 A1, 2011 ; WO 2011/071716 A1

上下游产品

上游产品  5
24424-99-5 45434-02-4 204376-48-7 6914-80-3
3697-69-6
下游产品  1
877204-21-2

海关

海关编码	2924299090
中文概述	2924299090. 其他环酰胺（包括环氨基甲酸酯）（包括其衍生物以及他们的盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
申报要素	品名, 成分含量, 用途, 包装
Summary	2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%