1198408-35-3

• 常用中文名：4-(6-氨基吡啶-3-基)哌啶-1-甲酸叔丁酯
• 常用英文名：Tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate
• CAS号：1198408-35-3
• 分子式：C₁₅H₂₃N₃O₂
• 分子量：277.362
• 相关类别： 医药中间体 杂环化合物 吡啶类化合物 氨基吡啶
• 发布时间：2018-12-25 13:11:23
• 更新时间：2024-01-09 19:59:41

名称

• 中文名: 4-(6-氨基吡啶-3-基)哌啶-1-甲酸叔丁酯
• 英文名: tert-butyl 4-(6-aminopyridin-3-yl)piperidine-1-carboxylate
• 中文别名: 4-(6-氨基吡啶-3-基)哌啶-1-羧酸叔丁酯
• 英文别名: 6-amino-3',4',5',6'-tetrahydro-2'H-3,4'-bipyridinyl-1'-carboxylic acid tert-butyl ester; 1-piperidinecarboxylic acid, 4-(6-amino-3-pyridinyl)-, 1,1-dimethylethyl ester

物化性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 422.8±45.0 °C at 760 mmHg
• 分子式: C₁₅H₂₃N₃O₂
• 分子量: 277.362
• 闪点: 209.5±28.7 °C
• 精确质量: 277.179016
• PSA: 69.18000
• LogP: 2.00
• 蒸汽压: 0.0±1.0 mmHg at 25°C
• 折射率: 1.553
• 储存条件: 2-8°C，避光干燥密封

安全

• 海关编码: 2933990090

合成路线

1231930-22-5 ~99% 1198408-35-3

文献：F. HOFFMANN-LA ROCHE AG; BROTHERTON-PLEISS, Christine; JAIME-FIGUEROA, Saul; LOPEZ-TAPIA, Francisco Javier; LOU, Yan; OWENS, Timothy D. Patent: WO2013/24078 A1, 2013 ; Location in patent: Page/Page column 57; 58 ;

1279030-84-0 ~58% 1198408-35-3

文献：Cho, Young Shin; Borland, Maria; Brain, Christopher; Chen, Christine H.-T.; Cheng, Hong; Chopra, Rajiv; Chung, Kristy; Groarke, James; He, Guo; Hou, Ying; Kim, Sunkyu; Kovats, Steven; Lu, Yipin; O'Reilly, Marc; Shen, Junqing; Smith, Troy; Trakshel, Gary; Voegtle, Markus; Xu, Mei; Xu, Ming; Sung, Moo Je Journal of Medicinal Chemistry, 2010 , vol. 53, # 22 p. 7938 - 7957

375853-82-0 ~% 1198408-35-3

文献：F. HOFFMANN-LA ROCHE AG; BROTHERTON-PLEISS, Christine; JAIME-FIGUEROA, Saul; LOPEZ-TAPIA, Francisco Javier; LOU, Yan; OWENS, Timothy D. Patent: WO2013/24078 A1, 2013 ;

39856-50-3 ~% 1198408-35-3

文献：Hoffmann-La Roche Inc.; Brotherton-Pleiss, Christine E.; Lopez-Tapia, Francisco Javier; Lou, Yan Patent: US2013/150360 A1, 2013 ;

1072-97-5 ~% 1198408-35-3

文献：Cho, Young Shin; Borland, Maria; Brain, Christopher; Chen, Christine H.-T.; Cheng, Hong; Chopra, Rajiv; Chung, Kristy; Groarke, James; He, Guo; Hou, Ying; Kim, Sunkyu; Kovats, Steven; Lu, Yipin; O'Reilly, Marc; Shen, Junqing; Smith, Troy; Trakshel, Gary; Voegtle, Markus; Xu, Mei; Xu, Ming; Sung, Moo Je Journal of Medicinal Chemistry, 2010 , vol. 53, # 22 p. 7938 - 7957

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%