101342-45-4

• 常用中文名：盐酸差向金霉素
• 常用英文名：4-epi-Chlortetracycline Hydrochloride
• CAS号：101342-45-4
• 分子式：C₂₂H₂₄Cl₂N₂O₈
• 分子量：515.341
• 相关类别： 原料药 抗生素类药物 四环素类药
• 发布时间：2018-07-14 03:06:03
• 更新时间：2024-01-14 08:19:14

名称

• 中文名: 盐酸叉向金霉素
• 英文名: 4-epichlortetracycline hydrochloride
• 中文别名: 盐酸差向7-氯-4二甲胺五羟基-6-甲基-1,11-二氧-2-萘并萘羰酰胺; 盐酸差向金霉素; 4-环氯四环盐酸盐
• 英文别名: 4-Epichlortetracycline hydrochloride,can be used as secondary standard; 4-Epichlortetracycline hydrochloride; 4-Epichlortetracycline hydrochloride,can be used as secondary standard 100MG; (4R,4aS,5aS,6S,12aS)-7-Chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide Monohydrate; 4-Epichlortetracycline hydrochloride,can be used as secondary standard 500MG; chlorotetracycline hydrochloride; 4-epi-Chlortetracycline Hydrochloride; (4R,4aS,5aS,6S,12aS)-7-Chloro-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-2-tetracenecarboxamide hydrochloride (1:1); MFCD00143314; 4-Epichlortetracycline hydrochlorideECTC; 2-Naphthacenecarboxamide, 7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, (4R,4aS,5aS,6S,12aS)-, hydrochloride (1:1); Chlortetracyclin-hydrochlorid; 4-Epichlortetracycline Hydrochlorid

物化性质

• 熔点: >250ºC
• 分子式: C₂₂H₂₄Cl₂N₂O₈
• 分子量: 515.341
• 精确质量: 514.090942
• PSA: 181.62000
• LogP: 1.94130
• 外观性状: Powder | Pale yellow to orange
• 储存条件:

  密闭于阴凉干燥环境中

• 稳定性:

  遵照规定使用和储存则不会分解。

• 分子结构:

  1、摩尔折射率：无可用

  2、 摩尔体积（cm³/mol）：无可用

  3、 等张比容（90.2K）：无可用

  4、 表面张力（dyne/cm）：无可用

  5、 极化率：无可用

• 更多:

  1. 性状：无可用

  2. 密度（g/mL,25/4℃）：无可用

  3. 相对蒸汽密度（g/mL,空气=1）：无可用

  4. 熔点（ºC）：大于250

  5. 沸点（ºC,常压）：无可用

  6. 沸点（ºC,5.2kPa）：无可用

  7. 折射率：无可用

  8. 闪点（ºC）：无可用

  9. 比旋光度（º）：无可用

  10. 自燃点或引燃温度（ºC）：无可用

  11. 蒸气压（kPa,25ºC）：无可用

  12. 饱和蒸气压（kPa,60ºC）：无可用

  13. 燃烧热（KJ/mol）：无可用

  14. 临界温度（ºC）：无可用

  15. 临界压力（KPa）：无可用

  16. 油水（辛醇/水）分配系数的对数值：无可用

  17. 爆炸上限（%,V/V）：无可用

  18. 爆炸下限（%,V/V）：无可用

  19. 溶解性：无可用

MSDS

Name: 4-Epichlortetracycline hydrochloride can be used as secondary Material Safety Data Sheet Synonym: ECT CAS: 101342-45-4 Section 1 - Chemical Product MSDS Name:4-Epichlortetracycline hydrochloride can be used as secondary Material Safety Data Sheet Synonym:ECT Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 101342-45-4 4-Epichlortetracycline hydrochloride 97% unlisted Hazard Symbols: XN Risk Phrases: 63 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Possible risk of harm to the unborn child.Light sensitive.Moisture sensitive. Potential Health Effects Eye: Non-irritating to the eyes. Skin: Non-irritating to the skin. Ingestion: The toxicological properties of this substance have not been fully investigated. Inhalation: May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. Chronic: May cause reproductive and fetal effects. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Get medical aid. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Section 7 - HANDLING and STORAGE Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Use only in a chemical fume hood. Storage: Store in a cool, dry place. Do not store in direct sunlight. Store in a tightly closed container. Keep under a nitrogen blanket. Keep refrigerated. (Store below 4C/39F.) Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 101342-45-4: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Powder Color: light yellow - orange Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: >250 deg C(decom) Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: 1:15 m/v Specific Gravity/Density: Molecular Formula: C22H23ClN2O8.HCl Molecular Weight: 515.34 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Stable under normal temperatures and pressures. Conditions to Avoid: Incompatible materials, light, dust generation, exposure to air, exposure to moist air or water. Incompatibilities with Other Materials: Strong oxidizing agents. Hazardous Decomposition Products: Hydrogen chloride, nitrogen oxides, carbon monoxide, carbon dioxide. Hazardous Polymerization: Has not been reported. Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 101342-45-4 unlisted. LD50/LC50: Not available. Carcinogenicity: 4-Epichlortetracycline hydrochloride - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Not regulated as a hazardous material. IMO Not regulated as a hazardous material. RID/ADR Not regulated as a hazardous material. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XN Risk Phrases: R 63 Possible risk of harm to the unborn child. Safety Phrases: S 36/37 Wear suitable protective clothing and gloves. S 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). WGK (Water Danger/Protection) CAS# 101342-45-4: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 101342-45-4 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 101342-45-4 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A

毒性和生态

生态学数据: 该物质对环境可能有危害，对水体应给予特别注意。

安全

• 危害码 (欧洲): Xn:Harmful;
• 风险声明 (欧洲): R63
• 安全声明 (欧洲): S36/37-S45
• 海关编码: 29413000