4402-83-9

• 常用中文名：3-(2,6-二氯苯基)-5-甲基异噁唑-4-羧酸甲酯
• 常用英文名：Methyl 3-(2,6-dichlorophenyl)-5-methylisoxazole-4-carboxylate
• CAS号：4402-83-9
• 分子式：C₁₂H₉Cl₂NO₃
• 分子量：286.11100
• 发布时间：2018-12-28 10:41:35
• 更新时间：2024-01-08 16:17:39

名称

• 中文名: 3-(2,6-二氯苯基)-5-甲基异噁唑-4-羧酸甲酯
• 英文名: methyl 3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazole-4-carboxylate
• 英文别名: 3-<2,6-Dichlor-phenyl>-5-methyl-isoxazol-4-carbonsaeure-methylester; methyl 3-(2,6-dichlorophenyl)-5-methylisoxazole-4-carboxylate; 3-(2,6-Dichlorophenyl)-5-methyl-4-isoxazolylcarboxylic Acid Methyl Ester; 3-(2,6-Dichlorophenyl)-5-methylisoxazole-4-carboxylic acid methyl ester; 3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolecarboxylic acid,methyl ester

物化性质

• 密度: 1.37 g/cm3
• 沸点: 382.4ºC at 760 mmHg
• 熔点: 115ºC
• 分子式: C₁₂H₉Cl₂NO₃
• 分子量: 286.11100
• 闪点: 185.1ºC
• 精确质量: 284.99600
• PSA: 52.33000
• LogP: 3.74340
• 折射率: 1.561
• 储存条件: 室温

MSDS

Name: Methyl 3-(2 6-dichlorophenyl)-5-methylisoxazole-4-carboxylate 97% Material Safety Data Sheet Synonym: CAS: 4402-83-9 Section 1 - Chemical Product MSDS Name:Methyl 3-(2 6-dichlorophenyl)-5-methylisoxazole-4-carboxylate 97% Material Safety Data Sheet Synonym: Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 4402-83-9 Methyl 3-(2,6-dichlorophenyl)-5-methyl 97% unlisted Hazard Symbols: XI Risk Phrases: 36/37/38 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Irritating to eyes, respiratory system and skin. Potential Health Effects Eye: Causes eye irritation. Skin: Causes skin irritation. May be harmful if absorbed through the skin. Ingestion: May cause irritation of the digestive tract. May be harmful if swallowed. Inhalation: Causes respiratory tract irritation. May be harmful if inhaled. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Get medical aid. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Section 7 - HANDLING and STORAGE Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Storage: Store in a cool, dry place. Store in a tightly closed container. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 4402-83-9: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Solid Color: white crystalline solid Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 115 deg C Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C12H9Cl2NO3 Molecular Weight: 286 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Not available. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Reducing agents, oxidizing agents, bases. Hazardous Decomposition Products: Hydrogen chloride, chlorine, hydrogen cyanide, nitrogen oxides, carbon monoxide, carbon dioxide. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 4402-83-9 unlisted. LD50/LC50: Not available. Carcinogenicity: Methyl 3-(2,6-dichlorophenyl)-5-methylisoxazole-4-carboxylate - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA No information available. IMO No information available. RID/ADR No information available. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XI Risk Phrases: R 36/37/38 Irritating to eyes, respiratory system and skin. Safety Phrases: S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 37/39 Wear suitable gloves and eye/face protection. WGK (Water Danger/Protection) CAS# 4402-83-9: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 4402-83-9 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 4402-83-9 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A

安全

• 危害码 (欧洲): Xi: Irritant;
• 风险声明 (欧洲): R36/37/38
• 安全声明 (欧洲): S26
• 海关编码: 2934999090

合成路线

6579-27-7 105-45-3 ~85% 4402-83-9

文献：4SC Discovery GmbH Patent: US2012/196862 A1, 2012 ; Location in patent: Page/Page column 29 ;

25185-95-9 ~% 4402-83-9

文献：Ramana, P. Venkata; Reddy, A. Ram Journal of Heterocyclic Chemistry, 2012 , vol. 49, # 3 p. 621 - 627

83-38-5 ~% 4402-83-9

文献：Ramana, P. Venkata; Reddy, A. Ram Journal of Heterocyclic Chemistry, 2012 , vol. 49, # 3 p. 621 - 627

83-38-5 105-45-3 ~% 4402-83-9

文献：Hanson; Long; Nayler; Stove Journal of the Chemical Society. Perkin transactions 1, 1965 , p. 5976 - 5983

上下游产品

上游产品  4
6579-27-7 105-45-3 25185-95-9 83-38-5
下游产品  2
3919-76-4 4462-55-9

海关

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%