622369-46-4

• 常用中文名：4-(2,4-二氯-5-甲氧基苯氨)-7-氟-6-甲氧基喹啉-3-腈
• 常用英文名：4-[(2,4-Dichloro-5-methoxyphenyl)amino]-7-fluoro-6-methoxy-3-quinolinecarbonitrile
• CAS号：622369-46-4
• 分子式：C₁₈H₁₂Cl₂FN₃O₂
• 分子量：392.211
• 发布时间：2019-01-07 18:27:08
• 更新时间：2024-01-11 11:58:25

名称

• 中文名: 4-[(2,4-二氯-5-甲氧基苯基)氨基]-7-氟-6-甲氧基-3-喹啉甲腈
• 英文名: 4-(2,4-dichloro-5-methoxyanilino)-7-fluoro-6-methoxyquinoline-3-carbonitrile
• 中文别名: 4-(2,4-二氯-5-甲氧基苯氨)-7-氟-6-甲氧基喹啉-3-腈
• 英文别名: 4-(2,4-dichloro-5-methoxyanilino)-7-fluoro-6-methoxy-3-quinolinecarbonitrile; 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-7-fluoro-6-methoxy-3-quinolinecarbonitrile; 4-(2,4-dichloro-5-methoxyphenylamino)-7-fluoro-6-methoxyquinoline-3-carbonitrile; 3-Quinolinecarbonitrile, 4-[(2,4-dichloro-5-methoxyphenyl)amino]-7-fluoro-6-methoxy-; 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-7-fluoro-6-methoxyquinoline-3-carbonitrile; QC-5180

物化性质

• 密度: 1.5±0.1 g/cm3
• 沸点: 512.2±50.0 °C at 760 mmHg
• 分子式: C₁₈H₁₂Cl₂FN₃O₂
• 分子量: 392.211
• 闪点: 263.6±30.1 °C
• 精确质量: 391.029053
• PSA: 70.40000
• LogP: 5.47
• 蒸汽压: 0.0±1.3 mmHg at 25°C
• 折射率: 1.659

安全

• 海关编码: 2933499090

合成路线

98446-49-2 622369-40-8 ~68% 622369-46-4

文献：Boschelli, Diane H.; Wang, Yanong D.; Johnson, Steve; Wu, Biqi; Ye, Fei; Barrios Sosa, Ana Carolina; Golas, Jennifer M.; Boschelli, Frank Journal of Medicinal Chemistry, 2004 , vol. 47, # 7 p. 1599 - 1601

846023-47-0 ~55% 622369-46-4

文献：Wyeth Holdings Corporation Patent: US2005/43537 A1, 2005 ; Location in patent: Page/Page column 11 ;

366-99-4 ~% 622369-46-4

文献：Boschelli, Diane H.; Wang, Yanong D.; Johnson, Steve; Wu, Biqi; Ye, Fei; Barrios Sosa, Ana Carolina; Golas, Jennifer M.; Boschelli, Frank Journal of Medicinal Chemistry, 2004 , vol. 47, # 7 p. 1599 - 1601

622369-38-4 ~% 622369-46-4

文献：Boschelli, Diane H.; Wang, Yanong D.; Johnson, Steve; Wu, Biqi; Ye, Fei; Barrios Sosa, Ana Carolina; Golas, Jennifer M.; Boschelli, Frank Journal of Medicinal Chemistry, 2004 , vol. 47, # 7 p. 1599 - 1601

海关

海关编码	2933499090
中文概述	2933499090. 其他含喹琳或异喹啉环系的化合物〔但未进一步稠合的〕. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%