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220991-20-8生产厂家

220991-20-8价格

220991-20-8

220991-20-8结构式
220991-20-8结构式
  • 常用中文名:罗美昔布
  • 常用英文名:Lumiracoxib
  • CAS号:220991-20-8
  • 分子式:C15H13ClFNO2
  • 分子量:293.721
  • 相关类别: 生物化工 抑制剂 神经信号通路(Neuronal Signaling) COX 抑制剂
  • 发布时间:2018-08-23 07:01:28
  • 更新时间:2024-01-09 16:41:45
  • Lumiracoxib, also known as CGS 35189 and COX 189, is a COX-2 selective inhibitor non-steroidal anti-inflammatory drug, manufactured by Novartis and still sold in few countries, including Mexico, Ecuador and the Dominican Republic, under the trade name Prexige. Since its original approval, lumiracoxib has been withdrawn from the market in several countries, mostly due to its potential for causing liver failure (sometimes requiring liver transplantation). It has never been approved for use in the United States.

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中文名 罗美昔布
英文名 lumiracoxib
中文别名 2-[(2-氯-6-氟苯基)氨基」-5-甲基苯乙酸
鲁米昔布
英文别名 2-[(2-chloro-6-fluorophenyl)amino]-5-methyl-benzeneacetic acid
Prexige (Novartis)
2-(2-((2-chloro-6-fluorophenyl)amino)-5-methylphenyl)acetic acid
{2-[(2-Chloro-6-fluorophenyl)amino]-5-methylphenyl}acetic acid
Prexige
COX189
5-methyl-2-(2'-chloro-6'-fluoroanilino)phenylacetic acid
Joicela
Benzeneacetic acid, 2-[(2-chloro-6-fluorophenyl)amino]-5-methyl-
(2-((2-chloro-6-fluorophenyl)-amino)-5-methylphenyl)-acetic acid
Lumiracoxib
[14C]-Lumiracoxib
2-[2-(2-chloro-6-fluoroanilino)-5-methylphenyl]acetic acid
Lumiracoxib [USAN:INN]
密度 1.4±0.1 g/cm3
沸点 395.7±42.0 °C at 760 mmHg
熔点 139-141ºC
分子式 C15H13ClFNO2
分子量 293.721
闪点 193.1±27.9 °C
精确质量 293.061890
PSA 49.33000
LogP 3.90
外观性状 淡黄色固体
蒸汽压 0.0±1.0 mmHg at 25°C
折射率 1.628
储存条件 -20°C Freezer